One of the most intriguing games of Week 4 in the NFL will be played on Sunday, October 2, between the AFC divisional rivals, and here you can read the best Broncos vs. Raiders betting pick and odds.

Las Vegas is the only winless team after the opening three weeks of the new NFL season but is hoping to change that when Denver comes to Allegiant Stadium. The Raiders are slight -2.5 favorites on BetDSI Sportsbook, while the total is set at 45.5 points. These AFC West foes have met twice in 2021, and the Raiders won both games.

Broncos edged the 49ers in a strange affair

The Denver Broncos responded to the Week 1 road loss to the Seattle Seahawks with a pair of home wins over the Houston Texans and San Francisco 49ers. The Broncos are now sharing the top spot in the AFC West with the Kansas City Chiefs, but the way they beat the Niners last week was quite peculiar, to say at least. Namely, Denver won 11-10, a result that was seen only once before in NFL history, and the rivals combined for 17 punts in one of the best defensive games in recent years.

The Broncos perhaps didn’t deserve to win if we take only their offense into consideration, but their D was at the highest level with three forced turnovers and none committed on the other end. San Francisco led 10-5 before Melvin Gordon scored a 1-yard rushing TD to win it for the hosts. Russell Wilson had modest numbers as he completed 20 of 33 passes for 184 yards. Once again, Courtland Sutton proved to be Wilson’s favorite target – Sutton caught eight passes for 97 yards, the most in the game of all receivers. Denver eclipsed 100 rushing yards for the third straight time, while on defense, Josey Jewell dominated with nine tackles and a sack.

T Billy Turner (knee) and DT D.J. Jones (concussion) are questionable to face the Raiders on Sunday, while S Justin Simmons is out indefinitely with a quadriceps injury.

Raiders fell short to the Titans on the road

For the third time this season, the Las Vegas Raiders suffered a loss and it was a one-possession game. This time around, the Raiders fell short 24-22 to the Tennessee Titans on the road. Tennessee was way better in the opening half and had a 14-point lead at the interval, and even though Las Vegas scored 12 unanswered points in the second 30 minutes, that didn’t help them to get the first win of the season.

Derek Carr completed 26 of 44 passes for 303 yards, two touchdowns, and one interception. Mack Hollins had the best game of his career as he received eight passes for 158 yards and a touchdown. Josh Jacobs led the team with 66 rushing yards on 13 carries. Defensively, Maxx Crosby was solid with team-high nine total tackles and a sack.

WR Hunter Renfrow missed the last game going through the concussion protocol, and it is undetermined if he will be active for Sunday’s clash against the Broncos. C Andre James (concussion), LB Denzel Perryman (ankle), CB Rock Ya-Sin (knee), CB Nate Hobbs (concussion), and S Tre’von Moehrig (hip) are questionable to play on Sunday.



  • 12-3 ATS in the last 15 games after scoring less than 15 points in their previous game

Las Vegas:

  • 0-4 ATS in the last four games overall
  • 3-7 ATS in the last ten vs. AFC rivals

Denver Broncos vs. Las Vegas Raiders Pick  

Denver’s offense is certainly not what we expected to see when Russell Wilson came from Seattle, but their defense compensated for offensive woes thus far. Still, I am backing Wilson and the Broncos’ offense to get things going against the Raiders, who allow 25.7 ppg and 267.0 passing yards per game. With strong options in the air to work with, Wilson should go for 250+ yards in this one. Las Vegas is a bit better when it comes to run defense but they still allow 100+ yards to the rivals, so I have no doubt Denver will register its fourth consecutive game with 100+ rushing yards.

Pick: Take the Broncos at -2.5 (-110)

The Total

All three of Denver’s games so far in the season were low-scoring, but I think it’s going to be a bit different on Sunday. Las Vegas will have to be very aggressive on offense because they will be eager to record the first win of the campaign, and although Denver has the third-best pass defense, I think the hosts will score 2+ passing touchdowns here. Also, I am backing the Broncos to have their best offensive display of the year. Over is 7-3 in the Raiders’ last ten vs. AFC West opponents, while Over is 10-4 in Las Vegas’ previous 14 games following a straight-up loss.

Pick: Go Over 45.5 points (-110)