The Louisville Cardinals, ranked #23, are set to take on the Michigan State Spartans, ranked #11, in the second round of the NCAA Men's Division I Basketball Tournament. This game will be held at the KeyBank Center in Buffalo, NY. The Cardinals enter this postseason game with a regular season record of 23-10 and a conference record of 12-8. Michigan State holds a regular season record of 25-7 and a conference record of 15-6. In the 2025 postseason, the Spartans made it to the Elite Eight, losing to Auburn. Both teams are eager to advance in the tournament, making this game a pivotal moment for each squad. <h2>Louisville Cardinals vs Michigan State Spartans Game Day Info</h2> <ul><li>Sport: NCAA Men's Division I Basketball</li><li>Teams: Louisville Cardinals vs Michigan State Spartans</li><li>Venue: KeyBank Center, Buffalo NY</li><li>Date: Saturday, March 21, 2026</li><li>Betting Odds:         <ul><li>Louisville Spread: +3.5</li><li>Michigan State Spread: -3.5</li><li>Louisville MoneyLine: +152</li><li>Michigan State MoneyLine: -180</li><li>Over/Under: 150.5 (-112)</li></ul></li></ul> <h2>Louisville Cardinals Team Preview</h2> <p>The Louisville Cardinals have shown strong performance this season. They average 84.8 points per game, ranking them 24th. Their field goal percentage is 47.0, placing them 76th overall.</p> <p>On defense, the Cardinals struggle with steals and blocks, ranking 517th and 528th, respectively. However, their postseason stats show improvement in rebounds, averaging 41.0 per game, which ranks them 11th. The team also ranks 2nd in effective field goal percentage during the postseason.</p> <p>Ryan Conwell leads the team in scoring with an average of 18.7 points per game. J'Vonne Hadley contributes with 11.8 points and 5.2 rebounds per game. Sananda Fru is notable for his efficiency, shooting 75.9% from the field in the regular season.</p> <h2>Michigan State Spartans Team Preview</h2> <p>The Michigan State Spartans have shown strong offensive skills this season. They score 78.9 points per game, placing them 121st in the nation. Their field goal percentage is 47.1%, ranking them 69th, which indicates their ability to make shots effectively.</p> <p>On the defensive side, the Spartans struggle with steals, averaging only 5.1 per game. This ranks them 328th, showing room for improvement in creating turnovers. They also commit 16.3 fouls per game, which ranks 405th, indicating a need for more disciplined play.</p> <p>Michigan State's players contribute significantly, with Jeremy Fears Jr. leading in scoring at 15.7 points per game. Jaxon Kohler contributes with 9.1 rebounds per game, providing strength under the basket. Carson Cooper also adds value with a field goal percentage of 57.2%, making him a reliable shooter.</p> <h2>BTB Betting Pick</h2> <p>For the spread pick, Louisville at +3.5 is the choice. The Cardinals have shown strong offensive stats, ranking high in points per game and effective field goal percentage. Michigan State, while favored, has less impressive scoring stats, making Louisville a good pick against the spread.</p> <p>Regarding the over/under, the under 150.5 is the recommendation. Despite Louisville's high scoring, Michigan State plays at a slower pace with fewer possessions per game. This suggests a lower total score, making the under a safer choice.</p>

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