In the second of a three-game series between the Chicago White Sox (19-8) and the Boston Red Sox (15-11) at U.S. Cellular Field, Carlos Rodon (1-3, 4.33 ERA) and Clay Buchholz (0-3, 6.51 ERA) get the start. The White Sox won the last game 4-1, and Chicago leads the series 1-0. The game starts at 8:10 p.m. ET on Wednesday, May. 4 and will air on WPWR, NESN and ESPN.

In his last start, Rodon pitched 7.0 innings, giving up six runs (two unearned), striking out seven and walking one in a 6-3 loss to the Orioles. The Red Sox were also unsuccessful the last time Buchholz pitched. He struggled, going 6.1 innings, allowing five runs, striking out two and walking four in a 5-3 loss to the Braves.

Oddsmakers have not posted a morning line and the Over/Under (O/U) is presently unavailable.

So far this season, the White Sox are 1-0 against the Red Sox.

Predictions: SU Winner - BOS

Notes

Chicago has won 67% (8-4) of its games when leading after seven innings. However, Boston has won 69% (9-4) of its games when taking a late lead.

Having scored one run in their last game, the Red Sox are going to have to step it up if they want to win this matchup. The White Sox have a 13-0 record in games where opponents scored one run or less.

When they outhit their opponents, the Red Sox are 14-2. The White Sox have a 15-0 record when outhitting opponents.

Ranking 17th in runs, Chicago has earned 106 this season. Boston ranks sixth with 135 runs.

Chicago and Boston both rank in the top half of the league in walks. Chicago sits at 11th with 87 this season and Boston ranks 15th with 82.

The White Sox are 12-5 when they hit at least one home run. The Red Sox perform similarly when they hit one or more homers with a 10-6 record.