Mat Latos (5-0, 3.40 ERA) and Doug Fister (3-3, 4.22 ERA) start in the second of a three-game series between the Chicago White Sox (24-15) and the Houston Astros (16-24) at U.S. Cellular Field. The Astros won the last game 6-5, and Houston leads the series 1-0. Action begins at 8:10 p.m. ET on Wednesday, May. 18 and can be seen on CSCh and RTSW.

Latos pitched 5.1 innings in his last outing, surrendering five runs and walking five in a 6-5 defeat to the Rangers. Todd Frazier (.228, 23 Rs, 12 HRs, 32 RBIs, 2 SBs) had another good game yesterday, going 2 for 4. Fister went 7.0 innings, surrendering two runs and striking out three in a 5-3 win over the Indians in his most recent start. Jose Altuve (.338, 37 Rs, 9 HRs, 24 RBIs, 15 SBs) went 1 for 4 yesterday with one RBI.

The odds for Chicago and Houston are White Sox -115, while the Over/Under (O/U) is 8.5 as of now.

The Astros have the edge in the season series, 1-0.

Predictions: SU Winner - HOU

Notes

In their last game, the Astros won by a margin of one run. The White Sox are 6-6 in one-run games. The Astros have a 5-7 record in close games.

When leading after seven innings, Chicago is 11-6, while Houston is 5-11.

The Astros are coming off of a hot pitching game where they recorded 12 strikeouts. The White Sox have a record of 0-4 when they are struck out that many times or more.

When they outhit their opponents, the Astros are 10-3. The White Sox have a 19-2 record when outhitting opponents.

Ranking 12th in runs, Houston has earned 172 this season. Chicago ranks 10th with 173 runs.

Ranking eighth, Chicago is in the top 10 of the league in walks, notching 136 this season. Houston ranks in the top five at second with 164.

When the White Sox hit at least one home run, they are 16-11. When the Astros hit at least one homer, they have a 13-17 record.