Jose Quintana (5-3, 1.98 ERA) is on the hill for the Chicago White Sox (27-20) as they square off against Corey Kluber (3-5, 4.10 ERA) and the Cleveland Indians (24-20) in the last of a four-game series at U.S. Cellular Field. The Indians won the last game 6-2, and Cleveland leads the series 2-1. Action begins at 2:10 p.m. ET on Wednesday, May. 25 and can be seen on STOh and WGN.

Quintana pitched 6.1 innings in his most recent start, surrendering four runs and striking out five in a 4-1 defeat to the Royals. Adam Eaton (.295, 20 Rs, 3 HRs, 15 RBIs, 5 SBs) had another good game yesterday, going 2 for 4 with one run, one home run, and one RBI. Kluber went 7.0 innings, surrendering two runs, striking out six and walking two in a 4-2 win over the Red Sox in his last outing. Mike Napoli (.229, 26 Rs, 8 HRs, 30 RBIs, 1 SB) has been successful at the plate, going 2 for 4 yesterday with one run, two RBIs, and one stolen base.

The odds for Chicago and Cleveland are White Sox -115, while the Over/Under (O/U) is 7.5 as of now.

The Indians lead the season series, 3-2.

Predictions: SU Winner - CLE

Notes

The White Sox and the Indians hold winning records against the AL Central Division this season. The White Sox sit at 9-5 and the Indians have a 13-7 record.

The White Sox managed to give up five walks in their last game. They'll have to pick it up against the Indians who are coming in with a 10-1 record against opponents who give up that many walks or more.

It looks like the Indians have a slight leg up on the White Sox, as the Indians have won their last two games while the White Sox have lost their last two.

When they outhit their opponents, the Indians are 16-5. The White Sox have a 21-2 record when outhitting opponents.

Ranking 14th in runs, Chicago has earned 193 this season. Cleveland ranks seventh with 210 runs.

Ranking 13th, Cleveland is in the top half of the league in walks, notching 149 this season. Chicago ranks in the top 10 with 159.

The White Sox are 18-12 in games where they hit one or more home runs. The Indians are 15-13 when they hit at least one homer.