James Shields (2-7, 4.28 ERA) and the Chicago White Sox (29-29) go up against Max Scherzer (6-4, 3.87 ERA) and the Washington Nationals (35-23) in the second of a three-game interleague series at U.S. Cellular Field. The Nationals won the last game 10-5, and Washington leads the series 1-0. The game starts at 8:10 p.m. ET on Wednesday, Jun. 8 and will air on CSCh and MAS2.

Todd Frazier (.221, 36 Rs, 19 HRs, 42 RBIs, 5 SBs) went 1 for 3 yesterday with one run, one home run, and two RBIs. The Nationals were victorious over the Phillies 7-2 the last time Scherzer pitched. He went 8.0 innings, allowing two runs, striking out 11 and walking two. Bryce Harper (.249, 34 Rs, 13 HRs, 37 RBIs, 7 SBs) went 1 for 4 yesterday with three RBIs.

The Nationals are a -160 favorite for James Shields's Chicago White Sox debut. The total is 8.

Pick - Wash

Notes

When leading after seven innings, Washington is 16-8, while Chicago is 14-15.

The Nationals are coming into this meeting after a high-scoring game where they scored an impressive 10 runs. The White Sox have a 0-4 record when opponents score that many runs or more.

When they are outhit, the White Sox are 4-24. The Nationals have a 5-16 record when opponents outhit them.

Chicago ranks near the bottom of the league when it comes to home runs, hitting 52 this season. Washington ranks in the top five at fourth with 77.

Ranking 11th, Chicago is in the top half of the league in walks, notching 189 this season. Washington ranks in the top 10 at seventh with 204.

When the White Sox hit at least one home run, they are 20-17. When the Nationals hit at least one homer, they have a 28-12 record.