Mike Fiers (0-2, 5.91 ERA) and the Milwaukee Brewers (2-11) go up against Jason Marquis (0-1, 6.30 ERA) and the Cincinnati Reds (6-7) in the second of a four-game division series at Miller Park. The Brewers lost the last game 6-1, extending a six-game losing streak. The game starts at 8:10 p.m. ET on Tuesday, Apr. 21 and will air on FSN-OH and FSN-WI.

Fiers has a 3.08 ERA and a 1-3 record in his career against the Reds, and is up against a struggling Cincinnati offense that's hitting just .223 on the year. Adam Lind (.302, 3 Rs, 1 HR, 5 RBIs) went 1 for 3 yesterday. In his career against the Brewers, Marquis is 6-12 with a 5.85 ERA. He meets a less-than-stellar Milwaukee offense that's batting just .208. Joey Votto (.375, 9 Rs, 5 HRs, 12 RBIs, 2 SBs) has been doing well to start the season for the Reds, going 2 for 4 yesterday with one run, one home run, and two RBIs.

Milwaukee is a -133 favorite in this game and the Over/Under (O/U) is eight runs. The Brewers have a losing record of 1-5 when playing as the favorite and an overall money line of -883. Over the last 10 games, they have performed poorly when playing as the favorite (1-3). The Brewers are the best in the NL in walks allowed at home, giving up just 1.2 per game.

On the other side, the Reds have a subpar record of 3-6 when they are the underdog and are -156 overall with the money line. They have played poorly as the underdog as of late. They managed a 2-6 record when playing as the underdog and an SU record of 3-7. Cincinnati is a terror on the base paths, with an MLB-best 14 stolen bases.

So far this season, the Reds are 1-0 against the Brewers. The Brewers will take on a right-hander (Marquis) in this game. They have done very poorly against right-handed starting pitchers this season (2-7), especially at home where they have a 1-4 record. The right-handed Fiers will take the mound against the Reds, who have a 4-5 record against righty starters this season.

Predictions: SU Winner - CIN, O/U - Over

Notes

The Brewers are struggling at 2-8 in their division, while the Reds are 6-7.

Milwaukee has won 25% (1-3) of its games when leading after 7 innings. However, Cincinnati has won 50% (2-2) of its games when taking a late lead.

The Brewers managed to give up five walks in their last game. They'll have to pick it up against the Reds who are coming in with a 1-1 record against opponents who give up that many walks or more.

When they are outhit, the Brewers are 1-10. The Reds have a 2-4 record when opponents outhit them.

Ranking 30th in home runs, Milwaukee has hit four this season. Cincinnati ranks ninth with 13 home runs.

Milwaukee and Cincinnati both rank in the top half of the league in hits. Milwaukee sits at 13th with 7.17 hits per game and Cincinnati ranks 12th with 7.50.

Ranking 30th, Milwaukee is at the bottom of the league for its on-base plus slugging percentage (.554). Cincinnati ranks near the bottom at 25th with an OPS of .634.

When the Reds allow at least one home run, they are 5-6. When the Brewers allow one or more homers, they have a 0-8 record.