In the second of a four-game series between the Los Angeles Angels (5-8) and the Oakland Athletics (5-8) at Angel Stadium, Hector Santiago (1-1, 2.92 ERA) and Drew Pomeranz (1-1, 3.00 ERA) get the ball. The Athletics won the last game 6-3 and Oakland leads the series 1-0. The game starts at 10:05 p.m. ET on Tuesday, Apr. 21 and will air on CSN-CA and FSN-W.

Santiago has a 1.99 ERA and a 2-2 record in his career against the Athletics, but faces a solid Oakland offense that's hitting .278 on the year. Mike Trout (.354, 11 Rs, 3 HRs, 9 RBIs, 3 SBs) went 1 for 4 yesterday with two runs and one stolen base. In his career against the Angels, Pomeranz is 1-1 with a 3.24 ERA. He meets a struggling Los Angeles offense that's batting just .214. Billy Butler (.365, 8 Rs, 1 HR, 7 RBIs) has been doing well, going 2 for 3 yesterday.

Los Angeles is a -125 favorite in this game and the Over/Under (O/U) is eight runs. The Angels have a losing record of 3-5 when playing as the favorite and an overall money line of -292. The Angels are fourth in the AL in walks allowed at home with just 2.3 per game.

On the other side, the Athletics have a nice record of 3-2 when they are the underdog, but are -264 overall with the money line. Against divisional rivals, they are 5-5 SU and 2-2 as the underdog. The Athletics are known for their bats, hitting 49 extra base hits. Shifting to the pitching staff, they have the fifth-lowest road ERA in the AL at 3.00. They have a WHIP of 1.06 on the year, good for fifth in the league.

So far this season, the Athletics are 1-0 against the Angels.

Predictions: SU Winner - OAK, O/U - Over

Notes

This season, the Angels hold an even 5-5 record against AL West teams. The Athletics sit at 6-5 against these opponents.

Los Angeles has won 25% (1-3) of its games when leading after 7 innings. However, Oakland has won 29% (2-5) of its games when taking a late lead.

The Angels managed to give up four walks in their last game. They'll have to pick it up against the Athletics who are coming in with a 3-2 record against opponents who give up that many walks or more.

When they are outhit, the Angels are 1-7. The Athletics have a 1-4 record when opponents outhit them.

Both Los Angeles and Oakland are tied at 15th in home runs, hitting 12 this season.

Ranking 14th, Los Angeles is in the top half of the league in hits, notching 7.17 per game. Oakland ranks in the top five at third with 9.85.

Ranking 26th, Los Angeles is near the bottom of the league for its on-base plus slugging percentage (.621). Oakland ranks in the top five at fifth with an OPS of .774.

The Athletics are 1-4 in games where they allow one or more home runs. The Angels are 3-8 when they allow at least one homer.