Tyler Lyons (0-0, 0.00 ERA) and Kyle Hendricks (0-1, 5.23 ERA) are on the hill in the second of a four-game series between the St. Louis Cardinals (19-6) and the Chicago Cubs (13-11) at Busch Stadium. The Cardinals won the last game 10-9, continuing a seven-game winning streak. Action begins at 8:15 p.m. ET on Tuesday, May. 5 and can be seen on WGN, FSN-MW and MLB Network.

This is the first start for Lyons this season. He pitched 36.2 innings last season, finishing 0-4 with a 4.42 ERA, 1.20 WHIP, and 36 strikeoutsMatt Holliday (.329, 14 Rs, 1 HR, 14 RBIs, 2 SBs) had another good game yesterday, going 2 for 4 with two runs. Hendricks is 0-1 with a 3.06 ERA when pitching against the Cardinals. He is up against a good St. Louis offense which is hitting .269 this season. Miguel Montero (.298, 6 Rs, 3 HRs, 13 RBIs) has been successful at the plate, going 2 for 4 yesterday with one run and three RBIs.

St. Louis is a -125 favorite against Chicago and the Over/Under (O/U) for this game is sitting at seven runs. The Cardinals have recorded an overall money line of +1,078 and have shown high-level performance as a favorite this season with a record of 15-4. St. Louis is an impressive 8-2 as the favorite over its last 10 games. The Cardinals have seen a decline in scoring against teams inside their division, averaging 3.6 runs per game. They average 4.1 runs per game on the season. Crossing over to the pitching staff, opposing offenses have been stifled by the Cardinals, who have a team ERA of only 2.21.

In the other locker room, Chicago is coming in with an overall money line of +110 and an impressive record of 6-3 as the dog. They have been playing solid baseball as the underdog with a 4-2 record against fellow NL Central members, and a 10-7 record SU. The Cubs are tough outs for opponents, ranking fourth in the NL with 9.2 hits per road game. The Cubs are an excellent base stealing team with 28 stolen bases, ranking third in the MLB. The Cubs average 3.8 runs allowed per game, but does better whenever another team from the NL Central is on the schedule. They bring that runs allowed average down to 3.4 against division foes.

The Cardinals lead the season series, 2-1. The Cardinals have a great 10-1 record at home (16-4 overall) against right-handed starting pitchers, which is what they'll be facing when Hendricks takes the mound.

Predictions: SU Winner - STL, O/U - Over

Notes

The Cardinals sit at 14-4 against their divisional rivals, while the Cubs are 10-8.

When leading after 7 innings, St. Louis is 7-3, while Chicago is 5-5.

The Cardinals managed to give up seven walks in their last game. They'll have to pick it up against the Cubs who are coming in with a 1-1 record against opponents who give up that many walks or more.

The Cardinals are coming into the game with seven consecutive wins, while the Cubs currently have a losing streak of three.

When they outhit their opponents, the Cardinals are 12-5. The Cubs have an 8-2 record when outhitting opponents.

Ranking 16th, Chicago sits in the bottom half of the league in runs, scoring 103 this season. St. Louis ranks in the top half at 14th with 109.

St. Louis and Chicago both rank in the top 10 of the league in walks. St. Louis sits at ninth with 88 this season and Chicago ranks 10th with 86.

The Cardinals are 10-2 when they hit at least one home run. The Cubs perform similarly when they hit one or more homers with a 9-3 record.