In the first of a four-game series between the Los Angeles Angels (13-15) and the Houston Astros (13-15) at Angel Stadium, Hector Santiago (2-2, 3.14 ERA) and Collin McHugh (4-0, 3.41 ERA) get the start. The game gets underway at 10:05 p.m. ET on Thursday, May. 7 and will air on ROOT-SW and FSN-W.

Santiago is 0-2 with a 7.47 ERA against the Astros in his career, but faces a less-than-stellar Houston offense that's hitting just .238 on the year. Mike Trout (.300, 23 Rs, 7 HRs, 17 RBIs, 6 SBs) went 1 for 4 yesterday with one run, one home run, and two RBIs. In his career against the Angels, McHugh is 2-2 with a 1.90 ERA. He meets a struggling Los Angeles offense that's batting just .226.

Los Angeles, a +106 underdog, will look to capitalize at home against Houston. The teams combine to set the Over/Under (O/U) at seven runs. The Angels have a losing record of 4-7 when playing as the underdog and an overall money line of -496. Over the last 10 games, they have performed poorly when playing as the underdog (2-5). Within their division, Los Angeles's offense has been playing lights out, averaging 4.2 runs per game, well over their season average of 3.8.

On the other side, the Astros have a record of 5-6 when they are favored and are +870 overall with the money line. Over the past 10 matchups, they are 7-3 SU and have a 1-3 record when they were the favorite. They sport the top-ranked offense in the AL, averaging six runs per game. Houston is one of the top road hitting teams in the AL with an average of 10.7 hits per contest. The Astros have racked up 33 steals on the year, making them the most threatening base-running team in the league. The Astros are a problem for opposing batters, sporting a 3.22 ERA this season. They have a WHIP of 1.10, best in the MLB.

The Astros are 2-1 against the Angels this season. This game will feature McHugh (RHP) on the mound against the Angels, who have a 2-6 home and 7-13 overall record when they take on a right-handed starter. The left-handed Santiago will take the mound against the Astros. Against lefty starters this season, they've racked up an impressive 8-4 record overall and 3-1 on the road.

Predictions: SU Winner - HOU, O/U - Over


The Astros hold a 14-8 record in matchups against AL West Division rivals, while the Angels currently sit at 13-9 in these games.

When the Astros play into extra innings, they have a 3-0 record. The Angels are 0-1 when their games exceed nine innings.

The Astros are coming off of a hot pitching game where they recorded nine strikeouts. The Angels have a record of 3-7 when they are struck out that many times or more.

When they are outhit, the Angels are 4-11. The Astros have a 4-6 record when opponents outhit them.

Los Angeles ranks in the top half of the league at 12th when it comes to home runs, hitting 25 this season. Houston ranks in the top five at second with 42.

Ranking 15th, Los Angeles is in the top half of the league in hits, notching 7.41 per game. Houston ranks in the top 10 at 10th with 8.15.

Ranking 27th, Los Angeles is near the bottom of the league for its on-base plus slugging percentage (.641). Houston ranks in the top 10 at seventh with an OPS of .743.

When the Astros allow at least one home run, they are 5-7. When the Angels allow one or more homers, they have a 6-14 record.