Roenis Elias (0-1, 3.86 ERA) and the Seattle Mariners (15-17) meet Odrisamer Despaigne (2-1, 5.13 ERA) and the San Diego Padres (17-17) in the second of a two-game interleague series at Safeco Field. The Mariners won the last game 11-4 and Seattle leads the series 1-0. The game gets underway at 10:10 p.m. ET on Wednesday, May. 13 and will air on FSN-SD and ROOT-NW.

In his most recent outing, Elias pitched 7.0 innings, allowing three runs, striking out five and walking one in a 4-3 loss to the Angels. Nelson Cruz (.349, 23 Rs, 15 HRs, 29 RBIs, 1 SB) continued his strong season yesterday, going 2 for 4 with two runs, one home run, and two RBIs. The Padres were unsuccessful to the Diamondbacks 11-0 the last time Despaigne pitched. He went 5.0 innings, giving up eight runs, striking out one and walking one.

Seattle is a slight +105 underdog in this game and the Over/Under (O/U) is set at seven runs. The Mariners have a losing record of 3-6 when playing as the underdog and an overall money line of -644. Over the last 10 games, they have performed poorly when playing as the underdog (1-3). Seattle's pitchers struggle against teams that play in the National League. The Mariners have given up an average of 5.7 runs to opponents from the NL, well over their defense's season average of 4.4 runs per game. An area where the Mariners are particularly strong at home is striking batters out, where they average an AL-best 9.5 K's per home game.

Moving on to the opposing team, the Padres come into this game in an interesting position. They have a negative money line (-5) but have won more than 60 percent of games played as the favorite (10-6). They have played at the top of their game when rated as favorite recently. They managed a 4-1 record when playing as the favorite and an SU record of 6-4. When it comes to scoring runs, the Padres haven't performed as well against teams from the AL. During those games, they averaged three runs per game, below their 4.6 season average. San Diego is one of the top hitting teams in the league with 102 extra base hits. San Diego's pitching staff tends to perform poorly when they play AL opponents. They've allowed an average of 10.0 runs per game against teams from the AL, higher than their season average of 4.5.

The only other game between the two teams went Seattle's way. The Mariners will take on a right-hander (Despaigne) in this game and have an 11-12 record against right-handed starting pitchers this season. The left-handed Elias will take the mound against the Padres. Against lefty starters this season, they've racked up an impressive 6-3 record.

Predictions: SU Winner - SD, O/U - Over


When leading after 7 innings, Seattle is 7-2, while San Diego is 9-6.

The Mariners are coming into this matchup after a high-scoring game where they scored a whopping 11 runs. The Padres have a 0-4 record when opponents score that many runs or more.

It looks like the Mariners have a slight leg up on the Padres, as the Mariners have won their last four games while the Padres have lost their last two.

When they outhit their opponents, the Mariners are 7-6. The Padres have a 13-2 record when outhitting opponents.

Ranking 23rd, Seattle is near the bottom of the league in runs, scoring 128 this season. San Diego ranks in the top 10 at seventh with 157.

Ranking 22nd, Seattle is near the bottom of the league in walks, notching 85 this season. San Diego ranks in the bottom half at 18th with 95.

The Mariners are 12-9 in games where they hit one or more home runs. The Padres are 11-6 when they hit at least one homer.