Marco Estrada (1-2, 3.55 ERA) and Felix Hernandez (6-1, 2.30 ERA) are on the hill in the first of a three-game series between the Toronto Blue Jays (19-24) and the Seattle Mariners (18-22) at the Rogers Centre. Action begins at 7:07 p.m. ET on Friday, May. 22 and can be seen on ROOT-NW and RSN.

Estrada pitched 5.0 innings in his most recent start, surrendering two runs, striking out eight and walking four in a 6-5 defeat to the Astros. Josh Donaldson (.305, 31 Rs, 9 HRs, 28 RBIs, 2 SBs) went 1 for 5 yesterday with one run. Hernandez is 5-6 with a 4.80 ERA against the Blue Jays in his career. He is up against a quality Toronto offense that's batting .258. Brad Miller (.267, 12 Rs, 5 HRs, 14 RBIs, 3 SBs) has been successful at the plate, going 2 for 5 yesterday with one run.

Seattle takes on Toronto as a -140 favorite. The Over/Under (O/U) for the matchup is sitting at seven runs. The Blue Jays have recorded an overall money line of -748 and have shown a weak performance as an underdog this season with a record of 7-16. Toronto has recorded a disappointing 1-6 record as the underdog over its last 10 games. The Blue Jays have no trouble scoring as they lead the AL in offense with 5.1 runs per game. The Blue Jays lead the MLB in extra base hits with 143. Toronto's batters do not strike out very often at home, with only 6.2 per game. As for the pitchers, the Blue Jays are the fourth-best team in the AL at limiting hits during home games, allowing only 7.7 hits per game to their opponents this season.

In games where it is the favorite, Seattle has a 14-14 record and an overall money line of -833.

The Blue Jays have a bad 12-21 record against right-handed starting pitchers on the year, which is what they'll be facing when Hernandez takes the mound. Estrada (RHP) will be on the hill against the Mariners, who have a 14-17 record against right-handed starting pitchers.

Predictions: SU Winner - TOR, O/U - Over

Notes

In their last game, the Mariners lost by a margin of one run. The Blue Jays are 2-8 in one-run games. The Mariners have a 9-9 record in close games.

The Blue Jays are 1-0 in games that go into extra innings. Meanwhile, the Mariners are 3-3 in such matchups.

The Mariners managed to give up five walks in their last game. They'll have to pick it up against the Blue Jays who are heading in with an 8-1 record against opponents who give up that many walks or more.

When they outhit their opponents, the Mariners are 9-8. The Blue Jays have a 17-3 record when outhitting opponents.

Toronto ranks at the top of the league when it comes to runs with 223 this season. Seattle ranks near the bottom at 26th with 152.

Ranking 21st, Seattle is near the bottom of the league in walks, notching 107 this season. Toronto ranks in the top 10 at eighth with 141.

The Blue Jays are 16-10 in games where they hit one or more home runs. The Mariners are 15-12 when they hit at least one homer.