In the first of a three-game series between the Arizona Diamondbacks (19-21) and the Chicago Cubs (19-21) at Chase Field, Josh Collmenter (3-5, 5.36 ERA) and Jon Lester (4-2, 3.70 ERA) get the ball. The game starts at 9:40 p.m. ET on Friday, May. 22 and will air on CSN-CHI+ and FSN-AZ.

Collmenter is 1-0 with a 1.27 ERA and 0.94 WHIP against the Cubs in his career. Yasmany Tomas (.349, 10 Rs, 1 HR, 12 RBIs, 2 SBs) played well again yesterday, going 2 for 5 with one run and one RBI. In his pitching opportunities against the Diamondbacks, Lester is 1-0 with a 6.35 ERA. He meets a solid Arizona offense that's batting .268. Kris Bryant (.289, 21 Rs, 5 HRs, 27 RBIs, 4 SBs) went 1 for 4 yesterday with one run, one home run, and two RBIs.

Arizona is a +121 underdog in this game and the Over/Under (O/U) is set at eight runs. When playing as the underdog, the Diamondbacks have a 13-14 record and overall money line at +two. They are 5-2 as the underdog over their last 10 games. The Diamondbacks have one of the most prolific home offenses in the entire NL, averaging 5.0 runs per game. The Diamondbacks rank third in the NL in hits at home with 9.2 per game. They have been a terror on the base paths, ranking fifth in all of baseball with 37 steals.

Switching to the opposing bench, the Cubs come into this game with a win percentage of .591 when playing as the favorite (13-9) and an overall money line of +297. They have played at the top of their game when rated as favorite recently. They managed a 6-2 record when playing as the favorite and an SU record of 7-3. Chicago is a terror on the base paths, ranking second in the MLB with 39 stolen bases.

The Diamondbacks will take on a left-hander (Lester) in this game and have a 4-5 record against left-handed starting pitchers this season. Taking the hill against the Cubs will be the right-hander Collmenter. They sport an 18-14 record against righties.

Predictions: SU Winner - CHC, O/U - Over


After last game's shutout win against the San Diego Padres, the Cubs now have five shutouts this season. The Diamondbacks have been shut out in four games this season.

When the Cubs play into extra innings, they have a 5-1 record. The Diamondbacks are 3-2 when their games exceed nine innings.

After a weak showing last week where they got in seven hits, the Cubs need to step it up. The Diamondbacks have a record of 9-5 when opponents get seven hits or fewer.

When they outhit their opponents, the Diamondbacks are 13-4. The Cubs have a 12-3 record when outhitting opponents.

Ranking 16th in runs, Chicago has earned 169 this season. Arizona ranks fourth with 189 runs.

Ranking 18th, Arizona is in the bottom half of the league in walks, notching 113 this season. Chicago ranks in the top five at third with 147.

The Diamondbacks are 14-6 when they hit at least one home run. The Cubs perform similarly when they hit one or more homers with a 16-6 record.