In a game that could be a shootout, Odrisamer Despaigne (2-3, 6.11 ERA) and the San Diego Padres (21-25) are in Los Angeles to take on Matt Shoemaker (3-4, 6.29 ERA) and the Angels (23-22). This is the second of a three-game series at Angel Stadium. The Angels won the last game 4-3 and Los Angeles leads the series 1-0. Action begins at 10:05 p.m. ET on Tuesday, May. 26 and can be seen on FSN-SD and FSN-W.

Shoemaker pitched 6.0 innings in his last outing, surrendering seven runs (one unearned), striking out four and walking two in an 8-4 defeat to the Blue Jays. Mike Trout (.299, 34 Rs, 11 HRs, 25 RBIs, 8 SBs) went 1 for 4 yesterday. Despaigne went 6.0 innings, surrendering two runs, striking out four and walking two in a 3-0 defeat to the Cubs in his most recent start. Justin Upton (.289, 32 Rs, 12 HRs, 35 RBIs, 9 SBs) has been successful at the plate for the Padres, going 2 for 4 yesterday.

Los Angeles is a -145 favorite against San Diego and the Over/Under (O/U) for this game is sitting at eight runs. The Angels have an overall money line of -191 and a record as the favorite of 13-12. Los Angeles has gone winless in its last 10 as the favorite. The Angels have seen a decline in scoring against teams in the NL, averaging 2.6 runs per game. They average 3.8 runs per game on the season. Los Angeles's pitchers put it all together when National League teams are on the field. Its average runs allowed per game drops to 3.2 against NL teams, compared to its 3.9 season average. The Angels are the fourth-best team in the AL at limiting walks to their opponents, allowing only 2.7 walks per game so far this season.

As for their opponent, San Diego is coming in with an overall money line of -405 and a disappointing record of 9-17 as the underdog. They played poorly as the underdog over their last 10 games with a 1-6 record, and a 3-7 record SU. Offensively, the Padres have really sputtered in the last 10 games. They have decreased their season average of 4.3 runs per game by averaging 3.2 during that stretch. The Padres allow 4.6 runs per game, but does worse whenever an AL opponent is on the schedule. They bring that runs allowed average up to 8.6 against teams from the AL.

The Angels have the edge in the season series, 1-0. The Angels have a 15-18 record against right-handed starting pitchers on the year, which is what they'll be facing when Despaigne takes the mound. Shoemaker (RHP) will be on the hill against the Padres, who have a 15-19 record against right-handed starting pitchers.

Predictions: SU Winner - LAA, O/U - Over

Notes

In their last game, the Padres lost by a margin of one run. The Angels are 8-7 in one-run games. The Padres have a 6-8 record in close games.

The Angels are 1-1 in games that go into extra innings. Meanwhile, the Padres are 1-2 in such matchups.

The Padres are coming off of a hot pitching game where they recorded 11 strikeouts. The Angels have a record of 2-2 when they are struck out that many times or more.

When they outhit their opponents, the Angels are 16-6. The Padres have a 15-3 record when outhitting opponents.

Ranking 25th in runs, Los Angeles has earned 171 this season. San Diego ranks 12th with 196 runs.

Los Angeles and San Diego both rank near the bottom of the league in walks. Los Angeles sits at 24th with 111 this season and San Diego ranks 21st with 115.

When the Angels hit at least one home run, they are 15-12. When the Padres hit at least one homer, they have a 14-8 record.