Hector Santiago (3-3, 2.47 ERA) starts for the Los Angeles Angels (24-24) as they square off against Anibal Sanchez (3-5, 6.12 ERA) and the Detroit Tigers (28-21) in the second of a four-game series at Angel Stadium. The Angels won the last game 12-2 and Los Angeles leads the series 1-0. Action begins at 10:05 p.m. ET on Friday, May. 29 and can be seen on FSN-DET and FSN-W.

Santiago is 0-3 with a 2.02 ERA in his appearances against the Tigers, but goes up against a quality Detroit offense which is batting .274 this season. Mike Trout (.296, 36 Rs, 11 HRs, 25 RBIs, 8 SBs) went 1 for 4 yesterday with one run. Sanchez is 0-2 with a 2.61 ERA when pitching against the Angels. He is up against a below-average Los Angeles offense which is hitting just .237 this season. Rajai Davis (.267, 20 Rs, 1 HR, 10 RBIs, 11 SBs) went 1 for 4 yesterday.

Los Angeles is a slim -115 favorite at home against Detroit. The matchup has an estimated Over/Under (O/U) of eight runs. The Angels have an overall money line of -415 and a record as the favorite of 14-14. Los Angeles is a disappointing 1-3 as the favorite over its last 10 games. Los Angeles's batters do not strike out very often, with only 7.2 per game. Los Angeles's pitching staff has been doing poorly against opposing offenses during the last 10 games, allowing an average of 5.4 runs per game, well above its season average of 3.9. Opponents have consistently been struck out by the Angels, who rank fifth in the AL in strikeouts per home game with 8.6.

In games where it is the underdog, Detroit has a 10-7 record and an overall money line of +532. The Tigers are an excellent base stealing team with 42 stolen bases, ranking third in the MLB. Detroit's pitching staff is one of the top in the AL, with a 3.69 ERA. When it comes to issuing walks, the Tigers have the third-fewest in the AL with an average of just 2.5 walks allowed per game.

The Angels have the edge in the season series, 1-0. The Angels have a 16-20 record against right-handed starting pitchers on the year, which is what they'll be facing when Sanchez takes the mound. Santiago (LHP) will be on the hill against the Tigers, who have very good records against left-handed starting pitchers on the road and overall of 6-2 and 8-3, respectively.

Predictions: SU Winner - DET, O/U - Over

Notes

The Angels won their last game by a 10-run margin. In games decided by a margin of 10 runs or more, the Tigers are 2-2. The Angels are 2-0 in blowouts this season.

The Tigers are 3-1 in games that go into extra innings. Meanwhile, the Angels are 1-2 in such matchups.

The Tigers managed to give up four walks in their last game. They'll have to pick it up against the Angels who are heading in with an 8-2 record against opponents who give up that many walks or more.

When they outhit their opponents, the Angels are 17-7. The Tigers have a 24-4 record when outhitting opponents.

Ranking 21st, Los Angeles is near the bottom of the league in runs, scoring 187 this season. Detroit ranks in the top half at 13th with 206.

Ranking 22nd, Los Angeles is near the bottom of the league in walks, notching 118 this season. Detroit ranks in the top five at third with 165.

The Angels are 16-13 in games where they hit one or more home runs. The Tigers are 19-6 when they hit at least one homer.