Jose Quintana (2-6, 4.33 ERA) and the Chicago White Sox (24-28) go up against Kyle Ryan (1-0, 3.00 ERA) and the Detroit Tigers (28-27) in the first of a three-game division series at U.S. Cellular Field. The Tigers enter this series on a seven-game losing streak. The game gets underway at 8:10 p.m. ET on Friday, Jun. 5 and will air on FSN-DET and CSN-CHI+.

Quintana has a 4.30 ERA and a 4-3 record in his career against the Tigers, and is up against a strong Detroit offense that's hitting .269 on the year. In his career against the White Sox, Ryan is 1-0 with a 0.00 ERA, 1.17 WHIP, and one strike out. Miguel Cabrera (.333, 29 Rs, 11 HRs, 36 RBIs, 1 SB) went 1 for 4 yesterday with one RBI.

Chicago is a -132 favorite in this game and the Over/Under (O/U) is set at eight runs. The White Sox are 13-10 as the favorite and have an overall money line of -473. They have SU record of 5-5 and are unbeaten as the favorite (2-0) over their last 10 games. Division games have been tough for the White Sox. Chicago has only averaged 3.1 runs per game compared to its 3.7 season average.

Moving on to the away team, the Tigers come into this game with a win percentage of .500 when playing as the underdog (10-10) and an overall money line of -235. Over the past 10 matchups, they are 2-8 SU and have played poorly as the underdog with a 1-4 record. During the last 10 games, they averaged 2.3 runs per game, below their 4.0 season average. Detroit is one of the top hitting teams in the AL with an average of 9.1 hits per contest. Detroit is a terror on the base paths, ranking third in the MLB with 45 stolen bases. The Tigers are one of the top AL pitching staffs on the road, essentially shutting down opponents to the tune of four runs allowed per away game. They also allow just 2.6 walks per game, good for fourth in the AL.

This game will feature Ryan (LHP) on the mound against the White Sox, who have a 3-5 record when they take on a left-handed starter. The left-handed Quintana will take the mound against the Tigers, who have an 8-5 record against lefty starters this season.

Predictions: SU Winner - DET, O/U - Over


The Tigers hold an 18-10 record against the AL Central Division this season, while the White Sox have a 12-19 record against the division.

Chicago has won 56% (10-8) of its games when leading after 7 innings. However, Detroit has won 61% (14-9) of its games when taking a late lead.

Having scored one run in their last game, the White Sox are going to have to up their game if they want to win this matchup. The Tigers have a 14-0 record in games where opponents scored that many runs or fewer.

When they are outhit, the Tigers are 2-19. The White Sox have a 4-23 record when opponents outhit them.

Both falling near the bottom of the league based on total home runs this season, Chicago ranks 28th with 35 homers and Detroit is 23rd with 42.

Ranking seventh, Chicago is in the top 10 of the league in hits, notching 8.45 per game. Detroit ranks in the top five at second with 9.11.

Ranking 29th, Chicago is near the bottom of the league for its on-base plus slugging percentage (.651). Detroit ranks in the top five at fifth with an OPS of .737.

When the Tigers allow at least one home run, they are 10-18, well-matched with the White Sox who are 13-21 when allowing at least one homer.