Nathan Karns (4-3, 3.53 ERA) and Marco Estrada (5-3, 3.92 ERA) take the hill in the last of a three-game series between the Tampa Bay Rays (41-32) and the Toronto Blue Jays (38-35) at Tropicana Field. The Rays won the last game 4-3 and the series is currently tied 1-1. Action begins at 12:10 p.m. ET on Wednesday, Jun. 24 and can be seen on RSN and SunSports.

Karns pitched 5.1 innings in his most recent start, surrendering one run, striking out four and walking one in a 4-1 win over the Indians. Joey Butler (.338, 19 Rs, 6 HRs, 20 RBIs, 5 SBs) went 1 for 3 yesterday with one run and one RBI. When pitching against the Rays, Estrada is 0-1 with a 1.12 ERA, 1.12 WHIP, and seven strikeouts. Chris Colabello (.347, 29 Rs, 5 HRs, 26 RBIs, 2 SBs) has been successful at the plate for the Blue Jays, going 2 for 4 yesterday with one run and two RBIs.

Tampa Bay is a slim -111 favorite at home against Toronto. The Over/Under (O/U) is sitting at seven runs for this matchup. The Rays have an overall money line of +817 and a record as the favorite of 19-15. Within its division, Tampa Bay has a 7-7 record as favorite and an 18-15 record SU. Tampa Bay is one of the best in the MLB in terms of steals, swiping 55 bases. Crossing over to the pitching staff, the Rays are the fifth-best team in the league at limiting hits and walks to their opponents, recording a WHIP of 1.20 so far this season. Opponents have consistently been struck out by the Rays, who rank second in the AL in strikeouts per home game with 8.8.

In games where it is the underdog, Toronto has a 15-20 record and an overall money line of +189. They are 10-10 as the underdog against fellow AL East members, and 19-16 SU. Offensively, they average five runs per game on the road, which is the best in the AL. The Blue Jays have a dynamic offense, leading the league with 252 extra base hits. Toronto is excellent at drawing walks with 3.3 per game, ranking second in the AL.

The Rays have controlled the season series, 7-2. The Rays have a 26-24 record against right-handed starting pitchers on the year, which is what they'll be facing when Estrada takes the mound. Karns (RHP) will be on the hill against the Blue Jays, who have a 27-30 record against right-handed starting pitchers.

Predictions: SU Winner - TOR, O/U - Over

Notes

The Rays hold a 19-15 record this season against teams in the AL East Division. The Blue Jays' record in these matchups is 19-17.

When leading after 7 innings, Toronto is 21-14, while Tampa Bay is 15-13.

The Rays are coming into this game after allowing one walk during their last outing. The Blue Jays have a 7-8 record when opponents give up that many walks or fewer.

When they are outhit, the Blue Jays are 5-26. The Rays have a 7-21 record when opponents outhit them.

Tampa Bay ranks in the top half of the league at 14th when it comes to home runs, hitting 67 this season. Toronto ranks in the top five at fourth with 92.

Ranking 11th, Tampa Bay is in the top half of the league in hits, notching 8.21 per game. Toronto ranks in the top five at third with 9.15.

Ranking first in on-base plus slugging percentage, Toronto has an OPS of .785 this season. Tampa Bay ranks 19th with an OPS of .700.

The Blue Jays are 24-25 when they allow at least one home run. The Rays perform similarly when they allow one or more homers with a 16-23 record.