Michael Wacha (10-3, 2.77 ERA) starts for the St. Louis Cardinals (51-27) as they square off against Andrew Cashner (3-9, 4.22 ERA) and the San Diego Padres (38-43) in the second of a four-game series at Busch Stadium. The Padres won the last game 5-3 and San Diego leads the series 1-0. Action begins at 8:15 p.m. ET on Friday, Jul. 3 and can be seen on FSN-SD and FSN-MW.

Wacha pitched 6.0 innings in his most recent start, surrendering one run, striking out five and walking two in an 8-1 win over the Cubs. Jhonny Peralta (.301, 34 Rs, 11 HRs, 41 RBIs, 1 SB) continued his strong play yesterday, going 2 for 6. Cashner is 0-1 with a 3.68 ERA against the Cardinals in his career. He is up against a quality St. Louis offense that's batting .262.

St. Louis is a -164 favorite against San Diego and the Over/Under (O/U) for this game is sitting at six runs. The Cardinals have recorded an overall money line of +2,084 and have shown high-level performance as a favorite this season with a record of 42-15. St. Louis is an impressive 7-2 as the favorite over its last 10 games. The Cardinals are one of the best in the NL in terms of hits at home with a phenomenal 9.0 per game. St. Louis is one of the best in the NL in terms of walks, earning an average of 3.0 per game. As for the pitchers, opposing offenses have been stifled by the Cardinals, who have a team ERA of only 2.64. The Cardinals are the third-best team in the NL at limiting hits to their opponents, allowing only 8.2 hits per game so far this season. Opponents have consistently been struck out by the Cardinals, who rank fifth in the NL in strikeouts per game with 8.1.

In the other locker room, San Diego is coming in with an overall money line of -591 and a disappointing record of 16-25 as the underdog.

The Padres have the edge in the season series, 1-0. The Cardinals have a great 26-4 record at home (44-15 overall) against right-handed starting pitchers, which is what they'll be facing when Cashner takes the mound. Wacha (RHP) will be on the hill against the Padres, who have a 28-35 record against right-handed starting pitchers.

Predictions: SU Winner - STL, O/U - Over

Notes

For the 11th time this season, the Cardinals registered at least two errors in a game.

The Padres are 6-3 in games that go into extra innings. Meanwhile, the Cardinals are 6-5 in such matchups.

The Padres managed to give up six walks in their last game. They'll have to pick it up against the Cardinals who are heading in with a 5-2 record against opponents who give up that many walks or more.

When they outhit their opponents, the Padres are 27-7. The Cardinals have a 35-9 record when outhitting opponents.

Ranking 19th, St. Louis is in the bottom half of the league in runs, scoring 314 this season. San Diego ranks in the top half at 14th with 332.

Ranking 21st, San Diego is near the bottom of the league in walks, notching 207 this season. St. Louis ranks in the top half at 11th with 241.

When the Cardinals hit at least one home run, they are 31-11, well-matched with the Padres who are 25-14 when hitting one or more homers.