Ervin Santana (6-10, 3.54 ERA) and the Minnesota Twins (49-84) meet Jose Quintana (11-9, 2.77 ERA) and the Chicago White Sox (63-69) in the first of a four-game division series at Target Field. The Twins go into this series on a 13-game losing streak. The game starts at 8:10 p.m. ET on Thursday, Sep. 1 and will air on CSCh and FSN.

In his last start, Santana pitched 6.2 innings, allowing six runs, striking out four and walking five in an 8-7 loss to the Blue Jays. Brian Dozier (.269, 85 Rs, 32 HRs, 81 RBIs, 11 SBs) went 1 for 4 yesterday with one run, one home run, and two RBIs. The White Sox were victorious over the Mariners 9-3 the last time Quintana pitched. He went 7.2 innings, allowing two, striking out eight and walking one. Jose Abreu (.288, 52 Rs, 19 HRs, 74 RBIs) has been doing well, going 2 for 4 yesterday with one run, one home run, and one RBI.

Minnesota is a +117 underdog in this game, and the Over/Under (O/U) is set at eight runs. The Twins perform poorly as an underdog with a 37-66 record and have an overall money line of -2,484. Over their last 10 games, they have no wins either SU or when playing as the underdog (0-9). Within their division, Minnesota's offense has been struggling. Minnesota has only averaged 3.9 runs per game compared to its 4.5 season average. The Twins typically don't swing at bad pitches, which has led to an impressive 3.1 walks per game. Minnesota's pitching staff has fallen apart in the past 10 games. Its average runs allowed per game rose to 7.3 during that span, compared to its 5.5 season average. The Twins are fourth in the AL in walks allowed with just 2.8 per game.

On the other side, the White Sox have a record of 35-26 when they are favored and are -556 overall with the money line. Against divisional opponents, they are 20-32 SU, but have a 15-12 record when they were the favorite.

The White Sox had the upper hand against the Twins in their previous 12 games this season, earning a 9-3 record. The Twins will take on a left-hander (Quintana) in this game and have a 15-19 record against left-handed starting pitchers this season. The right-handed Santana will take the mound against the White Sox, who have a 48-56 record against righty starters this season.

Predictions: SU Winner - MIN, O/U - Over

Notes

The Twins and White Sox both hold losing records against teams in the AL Central. The Twins sit at 15-38 in these matchups and the White Sox have a 20-32 record.

When leading after seven innings, Chicago is 30-30, while Minnesota is 27-33.

The White Sox managed to give up four walks in their last game. They'll have to pick it up against the Twins who are heading in with a 24-21 record against opponents who give up that many walks or more.

When they outhit their opponents, the Twins are 36-11. The White Sox have a 45-13 record when outhitting opponents.

Ranking 26th in runs, Chicago has earned 535 this season. Minnesota ranks 14th with 603 runs.

Ranking 26th, Chicago is near the bottom of the league in walks, notching 371 this season. Minnesota ranks in the top half at 12th with 416.

The Twins are 40-46 in games where they hit one or more home runs. The White Sox are 46-41 when they hit at least one homer.