Stephen Strasburg (15-1, 2.63 ERA) starts for the Washington Nationals (65-44) as they square off against Matt Cain (3-6, 5.53 ERA) and the San Francisco Giants (62-47) in the second of a three-game series at Nationals Park. The Nationals won the last game 5-1, and Washington leads the series 1-0. Action begins at 7:05 p.m. ET on Saturday, Aug. 6 and can be seen on MASN and CSBA.

Strasburg pitched 6.0 innings in his most recent start, surrendering one run, striking out six and walking two in a 14-1 win over the Diamondbacks. Daniel Murphy (.356, 66 Rs, 21 HRs, 81 RBIs, 3 SBs) went 1 for 4 yesterday with one RBI. Cain went 5.0 innings, surrendering zero runs, striking out five and walking four in a 3-1 win over the Nationals in his last outing. Angel Pagan (.282, 43 Rs, 8 HRs, 40 RBIs, 10 SBs) went 1 for 4 yesterday with one run, one home run, and one RBI.

This one isn't expected to be close when Washington, a big -210 favorite, takes on San Francisco. According to the oddsmakers, the Over/Under (O/U) is currently eight runs. The Nationals have recorded an overall money line of +348 and have shown high-level performance as a favorite this season with a record of 56-29. Washington is an impressive 5-1 as the favorite over its last 10 games. The Nationals are one of the best in the MLB in terms of home runs with 146. Crossing over to the pitching staff, the Nationals are the third-best team in the league at limiting hits and walks to their opponents, recording a WHIP of 1.157 so far this season.

In games where it is the underdog, San Francisco has a 16-22 record and an overall money line of +111. When it comes to preventing batters from getting on base, the Giants are one of the best in the league with a WHIP of 1.223 for the season.

The Nationals lead the season series, 3-2. The Nationals have a 50-33 record against right-handed starting pitchers on the year, which is what they'll be facing when Cain takes the mound. Strasburg (RHP) will be on the hill against the Giants, who have a 38-33 record against right-handed starting pitchers.

Predictions: SU Winner - WAS, O/U - Over

Notes

San Francisco has won 57% (21-16) of its games when leading after seven innings. However, Washington has won 63% (27-16) of its games when taking a late lead.

Having scored one run in their last game, the Giants are going to have to step it up if they want to win this matchup. The Nationals have a 29-1 record in games where opponents scored one run or less.

When they outhit their opponents, the Giants are 43-11. The Nationals have a 50-11 record when outhitting opponents.

Ranking 14th, San Francisco sits in the top half of the league in runs, scoring 489 this season. Washington ranks in the top 10 at eighth with 520.

Ranking sixth, Washington is in the top 10 of the league in walks, notching 383 this season. San Francisco ranks in the top five with 390.

When the Nationals hit at least one home run, they are 51-24, well-matched with the Giants who are 39-23 when hitting one or more homers.