Mike Fiers (5-9, 3.87 ERA) and the Houston Astros (66-56) meet Brett Anderson (7-7, 3.48 ERA) and the Los Angeles Dodgers (67-53) in the first of a three-game interleague series at Minute Maid Park. The game gets underway at 8:10 p.m. ET on Friday, Aug. 21 and will air on SNLA, RTSW and MLBN.

In his most recent outing, Fiers pitched 5.1 innings, allowing zero runs (two unearned), striking out five and walking two in a 6-5 loss to the Tigers. George Springer (.264, 43 Rs, 13 HRs, 29 RBIs, 14 SBs) went 1 for 2 yesterday with one run and one stolen base. The Dodgers were victorious over the Reds 8-3 the last time Anderson pitched. He went 6.0 innings, allowing three runs, striking out three and walking two.

Houston, a -120 favorite, will look to capitalize at home against Los Angeles. The Over/Under (O/U) for the matchup is eight runs. The Astros are 39-28 as the favorite and have an overall money line of +545. They come into the game with notable records of 6-2 as the favorite and 11-3 SU against the NL. Houston has been struggling as of late. In the last 10 games, Houston has only averaged 2.9 runs per game compared to the 4.3 they've averaged on the season. The Astros lead the majors in home runs with 164. They have been a terror on the base paths, ranking third in all of baseball with 92 steals. Transitioning to the Houston defense and pitching staff, teams routinely struggle to score runs against the Astros, who allow an AL-low 3.7 runs per game. The Astros don't allow many hitters to get on base, ranking second in the league with a 1.19 WHIP.

On the other side, the Dodgers have a record of 7-5 when they are the underdog and are -1,185 overall with the money line. Interleague opponents have had a tough time keeping up with Los Angeles. The Dodgers have managed to go undefeated when ranked as the underdog this season with a record of 1-0 and an 8-6 record SU. The Dodgers are known for their power, smashing 148 home runs. The last 10 games have really brought the worst out of the Los Angeles pitchers. They allowed 4.8 runs per game during that span, which is higher than their season average of 3.7. They also allow just 8.2 hits per game, good for third in the NL. They also have some of the most overpowering arms in the NL with an average of 8.6 strikeouts per game.

This game will feature Anderson (LHP) on the mound against the Astros, who have a 23-20 record when they take on a left-handed starter. Taking the hill against the Dodgers will be the right-hander Fiers. They sport a 57-40 record against righties.

Predictions: SU Winner - Hou, O/U - Over

Notes

When leading after 7 innings, Houston is 27-20, while Los Angeles is 21-21.

The Dodgers managed to give up four walks in their last game. They'll have to pick it up against the Astros who are heading in with a 35-17 record against opponents who give up that many walks or more.

When they outhit their opponents, the Astros are 47-13. The Dodgers have a 50-10 record when outhitting opponents.

Ranking 14th, Los Angeles sits in the top half of the league in runs, scoring 502 this season. Houston ranks in the top 10 at ninth with 523.

Ranking first in walks, Los Angeles has earned 416 this season. Houston ranks seventh with 369 walks.

The Astros are 54-34 when they hit at least one home run. The Dodgers perform similarly when they hit one or more homers with a 52-34 record.