Chris Sale (11-7, 3.32 ERA), attemping to pick up his 200th strikeout of the season, takes the hill for the Chicago White Sox (56-63) as they square off against Felix Hernandez (14-7, 3.65 ERA) and the Seattle Mariners (56-65) in the first of a three-game series at Safeco Field. Action begins at 10:10 p.m. ET on Friday, Aug. 21 and can be seen on CSCh and RTNW.

Hernandez pitched 2.1 innings in his most recent start, surrendering 10 runs, striking out two and walking one in a 22-10 defeat to the Red Sox. Nelson Cruz (.320, 67 Rs, 36 HRs, 75 RBIs, 3 SBs) went 1 for 4 Wednesday. Sale went 7.0 innings, surrendering zero runs, striking out 15 and walking two in a 3-1 win over the Cubs in his last outing. Adam Eaton (.264, 71 Rs, 10 HRs, 32 RBIs, 12 SBs) has been successful at the plate, going 2 for 3 yesterday with one run, one RBI, and one stolen base.

Seattle is a -122 favorite against Chicago and the Over/Under (O/U) for this game is sitting at six runs. The Mariners have an overall money line of -1,636 and a record as the favorite of 32-38. Seattle is an impressive 4-1 as the favorite over its last 10 games. Seattle's pitching staff has been doing poorly against opposing offenses during the last 10 games, allowing an average of 6.8 runs per game, well above its season average of 4.5.

In games where it is the underdog, Chicago has a 27-39 record and an overall money line of -917. They played poorly as the underdog over their last 10 games with a 2-5 record, and a 4-6 record SU. The White Sox have a dynamic offense, ranking third in the league with 312 extra base hits. The White Sox allow 4.3 runs per game, but have improved upon those numbers in the past 10 games, allowing 3.0 runs per game during that span. When it comes to issuing walks on the road, the White Sox have the fewest in the AL with only 2.4 walks allowed per game. The White Sox have established a reputation of overwhelming hitters with an AL-best 8.3 strikeouts per game, making them one of the top five teams in the league.

The Mariners have a 14-20 record against left-handed starting pitchers on the year, which is what they'll be facing when Sale takes the mound. Hernandez (RHP) will be on the hill against the White Sox, who have a 45-49 record against right-handed starting pitchers.

Predictions: SU Winner - Sea, O/U - Under

Notes

Seattle has won 42% (19-26) of its games when leading after 7 innings. However, Chicago has won 48% (23-25) of its games when taking a late lead.

The White Sox are coming off of a weak pitching game where they recorded four strikeouts. The Mariners have a record of 5-5 when opponents' pitchers have that many strikeouts or fewer.

When they outhit their opponents, the Mariners are 35-18. The White Sox have a 44-12 record when outhitting opponents.

Seattle and Chicago both rank near the bottom of the league in runs. Seattle sits at 24th with 459 runs this season and Chicago ranks 29th with 445.

Ranking 28th, Chicago is near the bottom of the league in walks, notching 274 this season. Seattle ranks in the top half at 14th with 344.

When the Mariners hit at least one home run, they are 47-36, well-matched with the White Sox who are 35-32 when hitting one or more homers.