Jake Arrieta (15-6, 2.30 ERA) is on the hill for the Chicago Cubs (72-51) as they square off against Matt Cain (2-3, 5.66 ERA) and the San Francisco Giants (66-58) in the first of a three-game series at AT&T Park. The Cubs come into this series hoping to extend a five-game winning streak. Action begins at 10:15 p.m. ET on Tuesday, Aug. 25 and can be seen on WGN and CSBy.

Cain pitched 6.0 innings in his most recent start, surrendering two runs, striking out six and walking one in a 4-3 defeat to the Cardinals. Brandon Crawford (.267, 58 Rs, 19 HRs, 75 RBIs, 4 SBs) went 1 for 4 Sunday. Arrieta went 6.0 innings, surrendering zero runs, striking out seven and walking one in a 7-1 win over the Braves in his last outing. Anthony Rizzo (.291, 71 Rs, 25 HRs, 77 RBIs, 15 SBs) went 1 for 4 yesterday with one RBI.

Chicago takes on San Francisco as a -130 favorite. The Over/Under (O/U) for the matchup is sitting at six runs. The Giants have an overall money line of +254 and a record as the underdog of 30-29. San Francisco has recorded a disappointing 2-5 record as the underdog over its last 10 games. The Giants are the fifth-best team in the NL at limiting hits to their opponents, allowing only 8.3 hits per game so far this season.

In the other locker room, Chicago is coming in with an overall money line of +966 and an impressive record of 51-30 as the favorite. They played solid baseball as the favorite over their last 10 games with a 6-2 record, and a 7-3 record SU. Offensively, the Cubs have really picked up the pace in the last 10 games. They have exceeded their season average of 4.2 runs per game by averaging 6.8 during that stretch. Moving on to Chicago's pitching staff and defense, the The Cubs allow just three runs per road game, ranking them second in the NL. When it comes to preventing batters from getting on base, the Cubs are one of the best in the league with a WHIP of 1.20 for the season.

The Cubs have the edge in the season series, 4-0. The Giants have a 49-46 record against right-handed starting pitchers on the year, which is what they'll be facing when Arrieta takes the mound. Cain (RHP) will be on the hill against the Cubs, who have a 56-40 record against right-handed starting pitchers.

Predictions: SU Winner - ChC, O/U - Over


In their last game, the Cubs won by a margin of one run. The Giants are 15-18 in one-run games. The Cubs have a 28-17 record in close games.

The Giants managed to give up four walks in their last game. They'll have to pick it up against the Cubs who are coming in with a 38-14 record against opponents who give up that many walks or more.

It looks like the Cubs have a slight leg up on the Giants, as the Cubs have won their last five games while the Giants have lost their last two.

When they outhit their opponents, the Cubs are 45-8. The Giants have a 58-9 record when outhitting opponents.

Both falling in the top half of the league based on total runs this season, San Francisco ranks 11th with 532 runs and Chicago is 15th with 511.

Ranking first in walks, Chicago has earned 425 this season. San Francisco ranks 17th with 340 walks.

When the Giants hit at least one home run, they are 44-23, well-matched with the Cubs who are 48-22 when hitting one or more homers.