Mike Leake (9-6, 3.44 ERA) and the San Francisco Giants (68-59) meet Michael Wacha (15-4, 2.80 ERA) and the St. Louis Cardinals (82-45) in the first of a three-game series at AT&T Park. The Cardinals go into this series on a five-game winning streak. The game starts at 10:15 p.m. ET on Friday, Aug. 28 and will air on KNTV, FSMW and MLBN.

In his most recent outing, Leake pitched 6.0 innings, allowing one run, striking out six and walking one in a 3-2 loss to the Pirates. The Cardinals were victorious over the Padres 10-3 the last time Wacha pitched. He went 6.0 innings, giving up one run, striking out three and walking two. Matt Carpenter (.258, 74 Rs, 19 HRs, 67 RBIs, 3 SBs) went 1 for 4 yesterday with one run and one RBI.

San Francisco is a +110 underdog in this game and the Over/Under (O/U) is six runs. The Giants are 30-30 as the underdog and have an overall money line of +354. Over the last 10 games, they have performed poorly when playing as the underdog (1-6).

Switching to the opposing bench, the Cardinals come into this game with a solid win percentage of .701 when playing as the favorite (68-29) and an overall money line of +2,571. The Cardinals are a problem for opposing batters, sporting an NL-low 2.98 ERA on the road this season.

In their previous three games this season, the Cardinals have a 2-1 record. This game will feature Wacha (RHP) on the mound against the Giants, who have a 51-47 record when they take on a right-handed starter. The right-handed Leake will take the mound against the Cardinals. Against righty starters this season, they've racked up an impressive 63-30 record.

Predictions: SU Winner - StL, O/U - Over


When leading after 7 innings, St. Louis is 28-17, while San Francisco is 30-20.

The Cardinals managed to give up six walks in their last game. They'll have to pick it up against the Giants who are heading in with a 5-3 record against opponents who give up that many walks or more.

When they outhit their opponents, the Cardinals are 50-14. The Giants have a 60-9 record when outhitting opponents.

Ranking 22nd, St. Louis sits near the bottom of the league in runs, scoring 507 this season. San Francisco ranks in the top half at 12th with 550.

Ranking 18th, San Francisco is in the bottom half of the league in walks, notching 351 this season. St. Louis ranks in the top 10 at eighth with 389.

The Giants are 46-23 when they hit at least one home run. The Cardinals perform similarly when they hit one or more homers with a 54-20 record.