Marco Estrada (11-8, 3.19 ERA) and Cody Anderson (2-3, 4.30 ERA) start in the second of a three-game series between the Toronto Blue Jays (74-57) and the Cleveland Indians (64-66) at the Rogers Centre. The Indians won the last game 4-2, continuing a six-game winning streak. Action begins at 7:07 p.m. ET on Tuesday, Sep. 1 and can be seen on STOh and RSN.

Estrada pitched 6.0 innings in his last outing, surrendering one run, striking out six and walking three in a 4-1 defeat to the Rangers. Josh Donaldson (.301, 101 Rs, 36 HRs, 108 RBIs, 5 SBs) went 1 for 4 yesterday with two RBIs. Anderson went 4.1 innings, surrendering two runs, striking out four and walking two in a 6-2 defeat to the Brewers in his most recent start. Jason Kipnis (.319, 75 Rs, 7 HRs, 45 RBIs, 11 SBs) went 1 for 4 yesterday with one run.

This one isn't expected to be close when Toronto, a big -185 favorite, takes on Cleveland. According to the oddsmakers, the Over/Under (O/U) is currently nine runs. The Blue Jays have recorded an overall money line of +852 and have shown high-level performance as a favorite this season with a record of 55-28. Toronto is an impressive 7-2 as the favorite over its last 10 games. The Blue Jays have no trouble scoring as they lead the AL in offense with 5.5 runs per game. The Blue Jays lead the MLB in home runs with 184. As for the pitchers, opposing offenses that come to the Rogers Centre have been stifled by the Blue Jays, who have a team ERA of only 3.19 at home. The Blue Jays are the second-best team in the AL at limiting hits during home games, allowing only 7.7 hits per game to their opponents this season.

In games where it is the underdog, Cleveland has a 19-26 record and an overall money line of -1,499. Offensively, the Indians have really picked up the pace in the last 10 games. They have exceeded their season average of 4.1 runs per game by averaging 5.4 during that stretch. Cleveland is excellent at not striking out n the road with just 7.2 per game, ranking third in the AL. The Indians allow 4.1 runs per game, but have improved upon those numbers in the past 10 games, allowing 3.0 runs per game during that span. When it comes to preventing batters from getting on base, the Indians are one of the best in the league with a WHIP of 1.19 for the season.

The Indians lead the season series, 3-2. The Blue Jays have a 55-44 record against right-handed starting pitchers on the year, which is what they'll be facing when Anderson takes the mound. Estrada (RHP) will be on the hill against the Indians, who have a 47-39 record against right-handed starting pitchers.

Predictions: SU Winner - Tor, O/U - Over

Notes

When leading after 7 innings, Toronto is 35-24, while Cleveland is 20-22.

The Indians are coming into this game after allowing two walks during their last outing. The Blue Jays have a 23-24 record when opponents give up that many walks or fewer.

When they outhit their opponents, the Indians are 54-10. The Blue Jays have a 59-7 record when outhitting opponents.

Toronto ranks at the top of the league when it comes to runs with 720 this season. Cleveland ranks in the bottom half at 16th with 534.

Toronto ranks at the top of the league when it comes to walks with 448 this season. Cleveland ranks in the top five at second with 445.

When the Blue Jays hit at least one home run, they are 68-29, well-matched with the Indians who are 47-26 when hitting one or more homers.