Anthony DeSclafani (9-11, 3.79 ERA) and Noah Syndergaard (8-7, 3.39 ERA) start in the second of a four-game series between the Cincinnati Reds (63-89) and the New York Mets (86-67) at the Great American Ball Park. The Reds lost the last game 6-4, continuing a five-game losing streak. Action begins at 7:10 p.m. ET on Friday, Sep. 25 and can be seen on FSOH and SNY.

DeSclafani pitched 4.1 innings in his last outing, surrendering four runs (one unearned) and striking out three in an 8-4 defeat to the Brewers. Joey Votto (.316, 93 Rs, 29 HRs, 76 RBIs, 11 SBs) continued his strong play yesterday, going 2 for 3. Syndergaard went 6.0 innings, surrendering five runs and striking out eight in a 5-0 defeat to the Yankees in his most recent start. Yoenis Cespedes (.292, 99 Rs, 35 HRs, 105 RBIs, 7 SBs) has been successful at the plate for the Mets, going 2 for 4 yesterday with one run and two RBIs.

New York takes on Cincinnati as a -125 favorite. The Over/Under (O/U) for the matchup is sitting at eight runs. The Reds have recorded an overall money line of -2,325 and have shown a weak performance as an underdog this season with a record of 34-63. Cincinnati leads the MLB in steals, swiping 131 bases. Cincinnati's pitching staff has been doing poorly against opposing offenses during the last 10 games, allowing an average of 5.7 runs per game, well above its season average of 4.5.

As for their opponent, New York is coming in with an overall money line of +923 and an impressive record of 68-30 as the favorite. Offensively, they average four runs per game on the road, which is fifth in the NL. The Mets are tough outs for opponents, ranking fifth in the NL with 8.9 hits per road game. New York's pitching staff is one of the top in the NL, with a 3.52 ERA. When it comes to preventing batters from getting on base, the Mets are one of the best in the league with a WHIP of 1.19 for the season.

The Mets have the edge in the season series, 4-0. The Reds have a 49-66 record against right-handed starting pitchers on the year, which is what they'll be facing when Syndergaard takes the mound. DeSclafani (RHP) will be on the hill against the Mets, who have a 69-52 record against right-handed starting pitchers.

Predictions: SU Winner - NYM, O/U - Over

Notes

Cincinnati has won 40% (23-35) of its games when leading after 7 innings. However, New York has won 60% (37-25) of its games when taking a late lead.

The Mets are coming into this game after allowing one walk during their last outing. The Reds have a 7-19 record when opponents give up that many walks or fewer.

When they outhit their opponents, the Reds are 48-17. The Mets have a 61-7 record when outhitting opponents.

Ranking 24th, Cincinnati is near the bottom of the league in runs, scoring 617 this season. New York ranks in the bottom half at 17th with 643.

Cincinnati and New York both rank in the top 10 of the league in walks. Cincinnati sits at seventh with 479 this season and New York ranks 10th with 462.

The Reds are 54-44 in games where they hit one or more home runs. The Mets are 59-28 when they hit at least one homer.