Dallas Keuchel (19-8, 2.47 ERA) starts for the Houston Astros (84-75) as they square off against Rubby De La Rosa (14-8, 4.56 ERA) and the Arizona Diamondbacks (78-81) in the first of a three-game series at Chase Field. Action begins at 9:40 p.m. ET on Friday, Oct. 2 and can be seen on FSAZ and RTSW.

De La Rosa pitched 5.2 innings in his most recent start, surrendering two runs (one unearned), striking out two and walking three in a 6-3 win over the Padres. Paul Goldschmidt (.317, 100 Rs, 31 HRs, 107 RBIs, 21 SBs) continued his strong play yesterday, going 2 for 3 with two runs and one RBI. Keuchel went 7.0 innings, surrendering one run, striking out 10 and walking two in a 4-2 win over the Rangers in his last outing. Evan Gattis (.246, 66 Rs, 27 HRs, 87 RBIs) has been successful at the plate, going 2 for 4 Wednesday.

Houston takes on Arizona as a -155 favorite. The Over/Under (O/U) for the matchup is sitting at eight runs. The Diamondbacks have an overall money line of +109 and a record as the underdog of 42-51. In interleague play, they have had a solid season, earning 7-3 and 10-7 records as the underdog and SU respectively. Arizona is one of the best in the MLB in terms of steals, swiping 131 bases. Arizona's pitching staff has been doing better against opposing offenses during the last 10 games, only allowing an average of 3.1 runs per game, well under their season average of 4.3.

In games where it is the favorite, Houston has a 54-44 record and an overall money line of -345. Houston has put in a great performance against National League opponents, coming in with a nice record SU ({betdsi.at.nl.su_record}) and as the favorite (7-2). Offensively, the Astros have really picked up the pace in interleague games. They have exceeded their season average of 4.4 runs per game by averaging 5.5 in those contests. The Astros have a dynamic offense, ranking second in the league with 515 extra base hits. The Astros are an excellent base stealing team with 116 stolen bases, ranking third in the MLB. The Astros allow 3.8 runs per game, but does better whenever an NL opponent is on the schedule. They bring that runs allowed average down to 3.0 against teams from the NL. When it comes to preventing batters from getting on base, the Astros are one of the best in the league with a WHIP of 1.20 for the season.

The Astros lead the season series, 2-1. The Diamondbacks have a 19-22 record against left-handed starting pitchers on the year, which is what they'll be facing when Keuchel takes the mound. De La Rosa (RHP) will be on the hill against the Astros, who have a 53-46 record against right-handed starting pitchers.

Predictions: SU Winner - Hou, O/U - Over

Notes

The Astros won their last game by a one-run margin. In games decided by one run, the Diamondbacks are 20-24. The Astros are 21-29 in close games this season.

When leading after 7 innings, Houston is 39-27, while Arizona is 31-27.

The Astros are coming into this game after allowing two walks during their last outing. The Diamondbacks have a 26-43 record when opponents give up that many walks or fewer.

When they outhit their opponents, the Diamondbacks are 54-20. The Astros have a 62-18 record when outhitting opponents.

Arizona and Houston both rank in the top 10 of the league in runs. Arizona sits at seventh with 708 runs this season and Houston ranks eighth with 699.

Ranking 12th, Houston is in the top half of the league in walks, notching 473 this season. Arizona ranks in the top 10 at 10th with 483.

When the Diamondbacks hit at least one home run, they are 56-35, well-matched with the Astros who are 71-46 when hitting one or more homers.