In the last of a three-game series between the Seattle Mariners (11-9) and the Houston Astros (6-15) at Safeco Field, Hisashi Iwakuma (0-2, 3.81 ERA) and Collin McHugh (1-3, 7.56 ERA) take the mound. The Mariners won the last game 11-1, and Seattle leads the series 2-0. The game starts at 10:10 p.m. ET on Wednesday, Apr. 27 and will air on RTSW and RTNW.

In his most recent outing, Iwakuma pitched 8.0 innings, giving up two runs, striking out three and walking one in a 5-2 victory over the Angels. Robinson Cano (.237, 11 Rs, 7 HRs, 21 RBIs) continued his strong season yesterday, going 2 for 4 with one run, one home run, and six RBIs. The Astros were unsuccessful against the Red Sox 6-2 the last time McHugh pitched. He went 4.0 innings, allowing five runs, striking out three and walking one. Colby Rasmus (.273, 11 Rs, 7 HRs, 18 RBIs, 1 SB) went 1 for 4 yesterday.

Oddsmakers have deemed this game a Seattle -130 matchup and the Over/Under (O/U) is presently 7.5.

So far this season, the Mariners are 2-0 against the Astros.

Predictions: SU Winner - HOU


The Mariners are even against AL West teams (7-7), but the Astros have lost all of their games against the division (0-5).

When leading after seven innings, Seattle is 5-2, while Houston is 0-8.

Having scored one run in their last game, the Astros are going to have to step it up if they want to win this matchup. The Mariners have a 3-0 record in games where opponents scored one run or less.

When they are outhit, the Astros are 0-11. The Mariners have a 2-7 record when opponents outhit them.

Both Seattle and Houston are tied at fifth in home runs, hitting 27 this season.

Ranking 27th, Seattle is near the bottom of the league in hits, notching 7.47 per game. Houston ranks in the bottom half at 18th with 8.15.

Ranking 22nd, Seattle is near the bottom of the league for its on-base plus slugging percentage (.703). Houston ranks in the top half at 13th with an OPS of .737.

When the Astros allow at least one home run, they are 4-12. When the Mariners allow one or more homers, they have a 7-6 record.