In the last of a three-game series between the San Francisco Giants (11-11) and the San Diego Padres (7-14) at AT&T Park, Jeff Samardzija (2-1, 3.00 ERA) and Andrew Cashner (1-1, 4.29 ERA) get the start. The Giants won the last game 1-0, and San Francisco leads the series 2-0. The game starts at 3:45 p.m. ET on Wednesday, Apr. 27 and will air on CSBA, FSSD and MLBN.

In his last start, Samardzija pitched 7.2 innings, allowing one run and striking out five in an 8-1 victory over the Marlins. Hunter Pence (.266, 12 Rs, 4 HRs, 14 RBIs) went 1 for 3 yesterday. The Padres were also victorious the last time Cashner pitched. He had a good outing, pitching 6.0 innings, allowing one run, striking out four and walking one in a 4-1 victory over the Cardinals. Wil Myers (.306, 10 Rs, 4 HRs, 9 RBIs, 2 SBs) went 1 for 4 yesterday.

The odds are San Francisco -160 for this game and the Over/Under (O/U) is currently 7.5. The Giants have one of the most prolific home offenses in the entire NL, averaging 5.0 runs per game. The Giants typically don't swing at bad pitches, which has led to an impressive 3.7 walks per game.

The previous two games have all gone San Francisco's way.

Predictions: SU Winner - SF

Notes

The Padres are struggling at 3-8 in their division, while the Giants sit at 7-9.

After last game's shutout win against San Diego, the Giants now have one shutout this season. The Padres have been shut out in six games this season.

Having scored one run in their last game, the Giants are going to have to step it up if they want to win this matchup. The Padres have a 1-1 record in games where opponents scored one run or less.

It looks like the Giants have a slight leg up on the Padres, as the Giants have won their last two games while the Padres have lost their last four.

When they outhit their opponents, the Padres are 5-2. The Giants have a 9-0 record when outhitting opponents.

Ranking 21st, San Diego sits near the bottom of the league in runs, scoring 76 this season. San Francisco ranks in the top five with 105.

Ranking 19th, San Diego is in the bottom half of the league in walks, notching 60 this season. San Francisco ranks in the top five at third with 82.

When the Giants hit at least one home run, they are 7-7. When the Padres hit at least one homer, they have a 7-1 record.