<p>The Eastern Illinois Panthers head to Tuscaloosa for a game against the Alabama Crimson Tide in Week 13 of the 2025 season. The game will be held at Saban Field at Bryant-Denny Stadium. It is scheduled for Saturday, November 22, 2025, at 2:00 PM and will air on the SEC channel.</p> <p>Eastern Illinois has struggled this season with a 0-2 record, both losses coming on the road. Alabama enters the game with a strong 8-2 record and is ranked 10th in both the AP and Coaches polls. The Crimson Tide has been solid at home, winning five out of six games at Saban Field this season.</p> <h2>Eastern Illinois Team Preview</h2> <p>The Eastern Illinois Panthers have had a tough start to their season. They played against the Northwestern Wildcats and lost 31-7. In that game, they managed only 13 first downs and 167 passing yards.</p> <p>In their season opener, the Panthers faced the Illinois Fighting Illini and were defeated 45-0. They had difficulty moving the ball, with just 9 first downs and 147 passing yards. Their rushing game also struggled, gaining only 49 yards.</p> <p>Quarterback Pierce Holley has been leading the offense, throwing for 314 yards in two games. The rushing attack has been limited, with Jay Pearson gaining 49 yards in two games. On defense, the team has given up 76 points in their first two games, indicating areas for improvement.</p> <h2>Eastern Illinois vs Alabama Game Day Info</h2> <ul><li>Sport: NCAA Football</li><li>Teams: Eastern Illinois Panthers vs. Alabama Crimson Tide</li><li>Venue: Saban Field at Bryant-Denny Stadium in Tuscaloosa, AL</li><li>Date: Saturday, November 22, 2025</li><li>Betting Odds: Eastern Illinois Spread +50.5 (-110), Alabama Spread -50.5 (-110), Total Over 57.5 (-105), Total Under 57.5 (-116)</li></ul> <h2>Alabama Team Preview</h2> <p>The Alabama Crimson Tide have shown strong performances at home this season. Their recent win over LSU Tigers 20-9 highlighted their defensive skills. However, they faced a narrow 23-21 loss against Oklahoma Sooners, despite gaining more first downs and passing yards.</p> <p>Offensively, the Crimson Tide have accumulated 316 points this season, placing them 37th in the rankings. Their passing game ranks 15th with 2,947 yards, while their rushing game sits at 117th. Ty Simpson, the quarterback, has thrown for 2,787 yards in 10 games, leading the team's offensive efforts.</p> <p>Injuries are a concern for Alabama, with several players listed as questionable, including linebacker Jah-Marien Latham and tight end Danny Lewis Jr. Defensive play remains a strong point for the team, with 20 sacks and 8 interceptions ranking them high nationally. As they prepare for upcoming games, staying healthy will be key to maintaining their performance level.</p> <h2>BTB Betting Pick</h2> <p>For the spread pick, Alabama is favored by 50.5 points against Eastern Illinois. Alabama's offense has scored 316 points this season, while Eastern Illinois has only scored 7 points. With Alabama's strong offense and Eastern Illinois' struggles, Alabama is likely to cover the -50.5 spread.</p> <p>The total for the game is set at 57.5 points. Alabama's defense has allowed 178 points this season, and Eastern Illinois has only scored 7 points. Given these stats, the game is likely to go under the total of 57.5 points.</p>

Eastern Illinois Panthers vs Alabama Crimson Tide Betting Pick & Prediction for 11/22

BetDSI

Bookmaker

Bet US

 Up to $250 in Free Bets + 100 Free Spins

Eastern Illinois Panthers vs Alabama Crimson Tide Betting Pick & Prediction for 11/22

BetDSI

Bookmaker

Bet US

BetOnline

Bovada