<p>The Buffalo Bills will travel to face the Carolina Panthers in Week 8 of the 2025 NFL season. The game is set to take place at Bank of America Stadium in Charlotte, North Carolina. Fans can catch the action on FOX at 1:00 PM on Sunday, October 26, 2025.</p> <p>The Bills have a record of 4-2 this season, with a road record of 1-1. Meanwhile, the Panthers hold a 4-3 record, remaining unbeaten at home with a 3-0 record. The weather forecast predicts a cool day with overcast clouds and a light breeze, which may impact gameplay on the outdoor field.</p> <h2>Buffalo Bills Team Preview</h2> <p>The Buffalo Bills are looking to bounce back after a couple of tough games. They lost to the Atlanta Falcons 24-14 on the road. In that game, Josh Allen threw for 180 yards with two touchdowns but also had two interceptions.</p> <p>James Cook has been the star in the backfield for the Bills. He ran for 87 yards against the Falcons and had 537 rushing yards so far this season. Cook has also found the end zone five times, making him a key player to watch.</p> <p>On the defensive side, the Bills have some strong performers. Ed Oliver recorded a sack in the game against the Falcons. The Bills will need their defense to step up to secure a win in their next game.</p> <h2>Bills vs Panthers Game Day Info</h2> <ul><li>Sport: NFL</li><li>Teams: Buffalo Bills vs. Carolina Panthers</li><li>Venue: Bank of America Stadium in Charlotte, NC USA</li><li>Date: Sunday, October 26, 2025</li><li>Betting Odds: Bills Moneyline -382, Panthers Moneyline +302</li></ul> <h2>Carolina Panthers Team Preview</h2> <p>The Carolina Panthers have been on a winning streak, claiming victory in their last three games. They recently secured a win against the New York Jets with a score of 13-6. Their defense played a key role, forcing two interceptions and keeping the Jets to just six points.</p> <p>In their game against the Dallas Cowboys, the Panthers edged out a close 30-27 victory. Their ground game was strong, amassing 216 rushing yards. Rico Dowdle led with 183 rushing yards, showing his importance to the team's offense.</p> <p>The Panthers' defense has been effective in recent games, even though they struggled earlier in the season. They had a tough loss against the New England Patriots, losing 42-13. However, their recent performances have shown improvement, particularly in creating turnovers and limiting opponents' scoring opportunities.</p> <h2>BTB Betting Pick</h2> <p>The Bills are favored by 7.5 points against the Panthers. Buffalo's offense ranks 2nd in scoring, while Carolina's defense is 29th in opponent scoring. Given these stats, the Bills should cover the -7.5 spread. The projected score is Buffalo 31, Carolina 17.</p> <p>The total for the game is set at 46.5 points. Buffalo's offense is strong, but their defense ranks 11th in opponent scoring. Carolina's offense ranks 22nd in scoring. With these factors, the total score should stay under 46.5 points. The projected total is 48, but the defensive strength suggests a lower outcome.</p>

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Buffalo Bills vs Carolina Panthers Betting Pick & Prediction for 10/26

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