Another inter-conference clash in Week 6 in the NFL is scheduled for Sunday, October 16, so feel free to check out the best Buccaneers vs. Steelers betting pick and odds.

Pittsburgh is desperate to avoid the fifth consecutive loss when they welcome Tampa Bay at Acrisure Stadium. The Buccaneers are -9.5 favorites on Bovada Sportsbook, while the total is set at 46 points. These inter-conference rivals haven’t met since 2019.

Buccaneers beat the Falcons to avoid the third straight loss

The Tampa Bay Buccaneers (3-2, 2-3 ATS) have played three home games in a row, and after losing to the opening two against the Packers and Chiefs, they responded with a 21-15 victory over the Atlanta Falcons. Tampa’s defense was excellent as it kept the visitors off the scoreboard for the first three quarters. The Bucs created a 21-0 lead up to that point and then relaxed a bit in the final 15 minutes but still got a W. Tampa Bay dominated the yards (420-261) and first downs (26-19).

Tom Brady completed 35 of 52 passes for 351 yards and one touchdown. Leonard Fournette caught that lone TD pass and finished with game-high 83 yards on ten receptions. The running back also led the team in rushing yards with 56 and a score on 14 attempts. Mike Evans and Chris Godwin combined for 142 receiving yards on ten catches (14 targets). Unlike the Falcons who had no sacks in this game, Tampa Bay recorded five. Antoine Winfield Jr. led the Bucs with eight tackles.

C Ryan Jensen (knee), RB Giovani Bernard (ankle), T Josh Wells (calf), G Aaron Stinnie (knee), DT Akiem Hicks (plantar fasciitis), and CB Logan Ryan (foot) are out indefinitely. WR Julio Jones (knee), TE Cameron Brate (concussion), WR Breshad Perriman (hamstring), WR Chris Godwin (hip), and CB Carlton Davis III (hip) are questionable to play on Sunday against Pittsburgh.

Steelers didn’t stand a chance against the Bills on the road

The Pittsburgh Steelers (1-4, 1-3-1 ATS) opened the season with a surprising road win over the Cincinnati Bengals, but since then, they suffered four consecutive losses. The most recent one against the Buffalo Bills on the road was the biggest of the year as Pittsburgh scored a season-low three and allowed season-high 38 points.

Kenny Pickett completed 34 of 52 passes for a career-high 327 yards and one interception. George Pickens led the Steelers with 83 receiving yards on six catches, while Diontae Johnson and Chase Claypool combined for 110 yards on ten receptions (22 targets). The run offense didn’t work in this one; Pittsburgh collected only 54 yards on 17 rushes. Defensively, Myles Jack led the team with six tackles, while James Pierre, Arthur Maulet, and Cameron Heyward had five apiece.

LB T.J. Watt (pectoral) is out and will not play on Sunday against Tampa Bay. CB Cameron Sutton (hamstring), CB Ahkello Witherspoon (hamstring), DT Larry Ogunjobi (back), S Terrell Edmunds (concussion), CB Levi Wallace (concussion), and TE Pat Freiermuth (concussion) are questionable.


Tampa Bay:

  • 11-4 ATS in the last 15 games following an ATS loss
  • 5-1 ATS in the last six road games
  • 6-1 ATS in the last seven games after allowing less than 150 yards passing in their previous game


  • 0-3-1 ATS in the last four games overall
  • 0-3-1 ATS in the last four games following a straight-up loss of more than 14 points

Tampa Bay Buccaneers vs. Pittsburgh Steelers Pick  

It looks like the Steelers just gave up and it’s definitely going to be a losing season for Mike Tomlin and his team. Their offense is one of the least efficient in the NFL with 15.4 ppg and considering the Steelers are facing Tampa’s D that allows 16.6 ppg, it’s going to be hard to score more than ten points on Sunday. The Buccaneers are not the offensive force they were in the last two years, but they have what it takes to beat Pittsburgh and its defense that allows 25.6 ppg. The trio of Brady-Fournette-Evans is more than enough to cover.

Pick: Take the Buccaneers at -9.5 (-110)

The Total

The Bucs’ offense will be fine in this one and will score 25+ points with ease, but I am worried that Pittsburgh’s offense isn’t good enough to contribute and help the Over bettors. The Steelers have the second-worst secondary in the league that is allowing 287.6 yards per game to the opposing receivers, so expect Brady to throw at least three TD passes. Still, I am going with a low-scoring affair because of the Steelers’ poor offense. Under is 6-2 in the Buccaneers’ last eight games following an ATS loss; Under is 4-1 in Tampa Bay’s previous five games overall, while Under is 5-1 in the Steelers’ last six home games.

Pick: Go Under 47.5 points (-135)