The MLB betting action goes on with Sunday night baseball from Busch Stadium in St. Louis, so we have prepared the best Giants vs. Cardinals betting pick along with the latest team stats, news, and odds update.  

San Francisco and St. Louis close down their seven-game regular-season series with the final clash of a three-game set in Missouri. The Giants and Cardinals split their first two games at Busch Stadium, and according to BetOnline Sportsbook, the visitors are -135 moneyline favorites with a total of 7.0 runs. 

The Gints just put an end to their six-game win streak                           

The San Francisco Giants beat the Cardinals 8-2 last Friday to extend their winning streak to six games. They snapped it with a 4-0 defeat in Saturday afternoon’s middle contest, falling to 20-13 on the season. 

San Francisco boasts the second-highest scoring offense in the majors, tallying 5.09 runs per game. The Giants rank seventh in batting average (.245), ninth in OPS (.708), and tenth in home runs (33). On the pitching side of things, the Gints carry a 3.41 ERA (6th in the MLB) and 1.24 WHIP (tied-17th). 

Carlos Rodon will toe the rubber Sunday, searching for his second straight victory. The 29-year-old lefty fanned 12 across six frames in an 8-5 victory to the Colorado Rockies last Monday, yielding two earned runs on six hits and a couple of free passes. Rodon is 4-1 with a 1.80 ERA, 0.91 WHIP, and 53/7 K/BB ratio in six starts and 35 innings of work.  

The Cards snapped a two-game skid            

The St. Louis Cardinals blanked the Giants on Saturday and improved to 18-15 on the season. It was their second win in the last seven outings, and three of their previous five losses have come against San Francisco. 

The Cards are scoring 4.31 runs per game (11th in the MLB). They rank 11th in batting average (.240), 13th in OPS (.692), and 18th in home runs (29). On the other side of the ball, St. Louis owns a 3.44 ERA (7th) and 1.23 WHIP (16th). 

Adam Wainwright will get the ball Sunday, and the 40-year-old right-hander is 3-3 with a 3.18 ERA, 1.29 WHIP, and 28/13 K/BB ratio in six starts and 34 innings of work. Wainwright missed his previous turn in St. Louis’ rotation due to COVID-19. Back on May 4, the veteran hurler tossed seven frames of a one-hit ball in a 10-0 thrashing of the Kansas City Royals. 


San Francisco: 

  • 6-1 in the last seven games overall 
  • 13-7 in the last 20 games on the road  

St. Louis:

  • 2-5 in the last seven games overall 
  • 1-5 in the last six games played on Sunday 

San Francisco Giants vs. St. Louis Cardinals Pick 

St. Louis sports the second-highest OPS against the lefties (.802), but the current Cardinals are slashing only .101/.217/.268 in 31 at-bats against Carlos Rodon. On the other side, the current Giants have 22 hits in 90 at-bats against Adam Wainwright. San Francisco has recorded a .252/.334/.378 triple-slash against the righties so far this season. 

Hereof, Sunday’s clash at Busch Stadium should be a tight one. Both teams can lean on their bullpens, so it’s hard to predict the outcome. I lean toward the visiting team because of Carlos Rodon, who’s been outstanding through his first six starts in 2022. He’s yet to allow more than a couple of runs in a game. 

Pick: Take San Francisco Giants at -135                      

The Total:

If both Carlos Rodon and Adam Wainwright continue with a strong performance, we should see a proper low-scoring affair. Busch Stadium is a typical pitcher-friendly ballpark, so I’m backing the under on the totals. 

Four of Rodon’s six starts this season have produced seven or fewer runs in the total. On the other side, the under is 4-2 in the Cardinals’ previous six games overall. Also, three of the last five encounters between the Gints and Cards have seen seven or fewer runs on the scoreboard. 

Pick: Go under 7.0 runs at -115