The penultimate day of the MLB regular season will be played on Tuesday, October 4, and we have an interesting divisional tilt, so make sure you check out the best Giants vs. Padres betting pick and odds.

San Francisco and San Diego will play the second of a three-game series at Petco Park, and the Padres are N/A moneyline favorites on BookMaker Sportsbook, while the total is set at N/A runs. These NL West rivals have met 16 times before this series, and the Padres lead 11-5. Game 1 of the current series will be played on Monday night.

Giants’ late push is not enough for the playoffs

The San Francisco Giants are surely the hottest team in the MLB right now, but the fact that they won 11 of the last 13 games will not help them to secure a playoff spot. It’s too late for the Giants, who experienced a disappointing season, but at least they will try to finish the campaign above a .500 record. San Francisco swept the Rockies twice in the last two weeks and then won the most recent series over the Arizona Diamondbacks.

The Giants needed ten innings to edge the D-Backs 4-3 at home. David Villar hit a two-run single in the 10th to give his team a victory. He was also the only Giant with a multi-hit display, as Arizona recorded 16 hits opposite San Francisco’s six. The Giants took a bullpen approach to start the game, but Jharel Cotton was credited with a win and improved to a 4-2 record.

Carlos Rodon (14-8) will start for the 32nd time this year when he faces the Padres on Tuesday. The 29-year-old left-hander owns a terrific 2.88 ERA, 1.03 WHIP, and 237/52 K/BB ratio over 178.0 innings of work.

Padres need one more win to clinch the playoff spot

The San Diego Padres lost the previous two series to the Los Angeles Dodgers and Chicago White Sox, but they still need just one more victory to secure a playoff place. San Diego is three wins ahead of the Milwaukee Brewers with three games to go (including Monday night games), and most probably, the Padres will clinch that spot.

San Diego lost two of three games to the White Sox at home. Even though they had eight hits opposite Chicago’s five, the Padres scored just a run in a 2-1 defeat. Juan Soto, Josh Bell, and Ha-Seong Kim registered a couple of hits apiece but combined for only one RBI. Blake Snell (8-10) took a loss after pitching for 6.0 innings and allowing a run on three hits with six strikeouts and a walk.

Sean Manaea (7-9) will get on the hill for the 28th time this year when he takes on San Francisco on Tuesday. The 30-year-old left-hander has a 5.15 ERA, 1.34 WHIP, and 150/49 K/BB ratio across 152.0 innings.


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San Francisco Giants vs. San Diego Padres Pick

The Giants are in better form right now and even though they are entering this duel without the imperative to get a win, I am backing them to do it. Sean Manaea struggled in the final two months of the season and is without a win in his last five starts. He started three times against the Giants (0-1) and registered a 4.76 ERA over 17.0 innings. On the other hand, Carlos Rodon experienced an impressive September and has better numbers against the Padres than Manaea vs. the Giants (1-2 in three starts with a 3.79 ERA in 19.0 innings). San Francisco is slightly better when it comes to batting against southpaws.

Pick: Take the Giants to win N/A

The Total

Both teams are actually better in batting against lefties, combining for 9.32 runs per nine innings. I know that Manaea and Rodon are probably not going to complete the game here, but I expect them to surrender multiple runs while on the mound. Four of the previous five H2H meetings went Over, while that was the case in three of the previous four H2H duels in San Diego. We have some excellent batters on each end, so I expect to see a high-scoring affair on Tuesday.

Pick: Go Over N/A runs