Facing off at 8:20 on Thursday, November 23rd is the San Francisco 49ers and Seattle Seahawks. This game will be played at Lumen Field in Seattle WA. Carrying the game is NBC. The odds for this week 12 NFC West matchup have the 49ers as the 6.5 point favorites against the spread. Read on to get our betting insights for this week 12 matchup.


The Pick: Seattle Seahawks +6.5

This game will be played at Lumen Field at 8:20 ET on Thursday, November 23rd.


  • We have this one finishing with a projected score of 26-25 in favor of the 49ers.
  • Our projections have Geno Smith finishing with 304.732 passing yards on 26.169/40.448 passing.
  • The 49ers are projected to finish with 377 yards of offense compared to the 362 yards for the Seahawks.

Can the 49ers Lock in a Road Win?

With an overall record of 7-3, the 49ers are 1st in the NFC-West. This record also has them 3rd in the NFC. On the road, San Francisco is 3-2 compared to a record of 4-1 at home. Against the spread, the 49ers have a record of 5-4-1. Their average scoring margin for the season is currently +12.2.

On offense, the 49ers are averaging 27.9 points per game, putting them 3rd in the NFL. As a team, San Francisco is 8th in the NFL in passing yards per game (254.3). Their passing yards per attempt figure of 9.1 is 1 in the league.

At 132.7 rushing yards per game, the 49ers are 6th in the NFL. This figure has come on an average of 30.3 attempts (6th).

In terms of yards allowed, the 49ers are 5th in the league while giving up 302.8 yards per contest. San Francisco’s defense has allowed 15.7 points per game, placing them 1st in the NFL.

Do the Seahawks Have a Shot at a Home Win?

During this season, the Seahawks have an overall record of 6-4, which has them 2nd in the NFC-West. Their performance includes 1-3 as underdogs and 5-1 when they are favored. The Seahawks currently hold a 5-4-1 record against the spread. Currently, their average scoring margin is -0.2.

On offense, the Seahawks are averaging 21.6 points per game, putting them 15th in the NFL. Seattle currently sits 16th in passing attempts and has an average of 6.7 yards per attempt (10). They are also ranked 13th in the league with 230.8 passing yards per game.

The Seahawks hold the 24th position in the NFL with 96.6 rushing yards per game. This average has come on an average of 23.5 rushing attempts (27th).

Looking at Seattle’s defense, they currently stand 18th in points allowed. Opponents have been averaging 21.8 points per game and 345.6 yards per contest against them.