Betting on today’s Fighting Irish and Cardinals game? Catch the action at KFC Yum! Center in Louisville, KY, as the Cardinals hosts this showdown at 7:00 ET on ESPNU. The over/under for this Atlantic Coast conference contest is set at 134.5 points, with Louisville being favored by -1.5 at home against Notre Dame.


The Pick: Louisville Cardinals -1.5

This game will be played at KFC Yum! Center at 7:00 ET on Wednesday, February 21st.


  • We have this one finishing with a projected score of 75-68 in favor of the Cardinals.
  • Not only will Louisville pick up the win, but look for them to cover at -1.5.
  • The over/under is currently sitting at 134.5 points, and we like the over with a projected 143 points.

Is a Win at Louisville Possible for the Fighting Irish?

Notre Dame will look to snap a seven-game road losing streak when they take on Louisville. So far this season, the Fighting Irish have gone 1-7 on the road, with an average scoring margin of -10.8.

Notre Dame enters this game with an overall record of 9-16, including a 3-10 mark in Atlantic Coast Conference play. In their last game, the Fighting Irish defeated Georgia Tech by a score of 58-55.

Notre Dame has an overall ATS record of 11-13 this season, but their record vs. the spread as the underdog is 9-7. On the road, the Fighting Irish are 5-3 vs. the spread this year and their last 10 road ATS mark is 6-3.

Today’s over/under line of 134.5 is higher than the average over/under line in Notre Dame’s games this year (132.8). On the season, the over/under record for the Fighting Irish is 7-17. So far, 19 of their games have finished with fewer points than today’s line. In their last three games, the average scoring total is 125 points and their over/under record over their last 10 games is 3-6.

The Notre Dame offense is coming off a game in which they scored 58 points vs. Georgia Tech. Overall their field goal percentage was 31.6% while connecting on 5 threes. Currently leading the team in scoring is Markus Burton who comes into today’s matchup averaging 16.2. Braeden Shrewsberry also heads into the game with a PPG average of 9.2.

Coming into today’s game, the Notre Dame defense is giving up an average of 65.3 points per contest. In today’s game vs. Louisville, the Notre Dame defense will be looking to do a better job avoiding putting opponents on the line. In their last game, Notre Dame made 17 free-throws vs. the Fighting Irish.

Are Louisville Ready for a Home Win?

After losing their last game to Pittsburgh by a score of 86-59, Louisville enters this game with an 8-18 record. They have gone 3-12 in Atlantic Coast Conference games compared to their 5-6 mark in non-conference games.

At home, the Cardinals have gone 7-9 this season, and they are 6-2 when favored. For the year, they have been favored in eight of their 26 games.

Against the spread, Louisville is currently sitting at .500 on the season with a record of 12-12-2. At home, their ATS mark is also at .500 with a record of 7-7-2. Over their last 10 games as the favorite, the Cardinals have gone just 3-6-1 vs. the spread.

Today’s over/under line of 134.5 is lower than the average over/under line in Louisville’s games this season (147.4). In their last three games, the over/under record is 1-2 and the average scoring total is 151 points.

Against Pittsburgh, the Louisville had a tough time putting up points compared to their season average of 73.4 points per game. They scored 59 points and posted a field goal percentage of 44.4% in the game. Mike James is leading the team in scoring at 13.5 points per contest. Brandon Huntley-Hatfield has also been a key contributor with a PPG average of 12.3 going into the game.

Looking at the Louisville defense, they will be looking for a better performance considering they are currently conceding 78.9 points per game (309th). So far, the Louisville defense is giving up an average of 8.4 offensive rebounds per game and are turning teams over 12.3 times per game (630th).