Week 9 of the 2021 CFB season brings a ton of interesting markets Saturday, October 23, so we’re taking a closer look at the Big 12 Conference battle at Boone Pickens Stadium in Stillwater to get you the best Kansas vs. Oklahoma State betting pick and odds. 

The Jayhawks are 0-4 in the conference play and sit bottom of the standings. They are massive 30.5-point road underdogs on MyBookie Sportsbook, while the totals sit at 54.5 points. The Jayhawks are winless in 11 straight meetings with the Cowboys, who have won three of their first four games in the conference play. 

Kansas scared the Sooners in Week 8

The Kansas Jayhawks (1-6; 1-5-1 ATS) are on a six-game losing streak following a 35-23 home loss to the No. 3 Oklahoma Sooners last Saturday. During their awful run, the Jayhawks have had some bright moments, and they battled bravely against the No. 3 team in the country.

Kansas outgained Oklahoma in total yards (412-398) and had the ball in possession for 35 and a half minutes. The Jayhawks kept the Sooners off the scoreboard in the first half, but it wasn’t enough for an upset. Freshman RB Devin Neal led the way for Kansas with 23 carries for 100 yards and a couple of touchdowns, while junior QB Jason Bean tossed for 246 yards and a TD.

At least, the Jayhawks kept their opponents below a 40-point mark for the first time since the opening week and a 17-14 win to South Dakota. Kansas is tallying only 17.6 points per game (123rd in the country) on 337.9 total yards (107th) while yielding 42.1 points in a return (127th) on 472.4 total yards (123rd).

Oklahoma State looks to get back to the winning ways 

The No. 15 Oklahoma State Cowboys (6-1; 5-2 ATS) entered Week 8 undefeated, looking to upset the odds as 7-point road dogs at Iowa State. They covered the spread but suffered a painful 24-21 loss, as the Cowboys had a 14-7 lead at halftime and a 21-17 lead with 8:36 left on the clock in the fourth quarter.

Junior signal-caller Spencer Sanders tossed for 225 yards and three touchdowns. The Cowboys held the Cyclones to a paltry 67 rushing yards on 33 totes, but they allowed Brock Purdy to complete 27 of his 33 pass attempts for 307 yards and a couple of scores.

Before a tough loss to the Cyclones, Oklahoma State had won three straight games over the top-25 teams by an average margin of 9.7 points. The Cowboys allow only 20.1 points per game (31st in the nation) on 316.7 total yards (19th).



  • 1-4 ATS in the last five games overall
  • 1-8-1 ATS in the last ten games on the road 

Oklahoma State:

  • 4-1 ATS in the last five games against Wyoming
  • 4-1-1 ATS in the last six home games played on Saturday

Kansas vs. Oklahoma State Pick

The Cowboys are one of the best defensive teams in the country. Also, they are killing it against the spread, covering in five straight outings and five of their previous seven showings as favorites of 30 or more points.

This is a tough spot for the Jayhawks, who blew their chance against the Sooners. Kansas surrendered 35 second-half points last Saturday, and the Jayhawks will have a tall task to put 20-plus points on the scoreboard against this Oklahoma State team.

Pick: Take Oklahoma State -30.5 at -110            

The Total:

The Cowboys’ offense is not exactly a high-octane one, but Mike Gundy’s boys still convert 40.7 percent of their 3rd downs while tallying 25.7 points per game. Keep in mind their scary schedule, as the Cowboys have defeated some tough defensive teams, including Baylor and Kansas State.

The Cowboys shouldn’t have any problems moving the ball against Kansas. The Jayhawks will probably have to lean on their passing offense for all 60 minutes, and I can only hope they will score some points in garbage time. Last year, Oklahoma State trounced Kansas 41-7 as a 21.5-point road fave, and the over is 5-1 in their last six meetings overall.

Pick: Go over 54.5 points at -110