Wednesday, 8:05 pm Eastern

The big news out of Chicago on Tuesday was the Cubs getting Rich Harden from the Oakland Athletics. He is expected to form a powerful one-two combination at the top of the Cubs pitching staff with Wednesday’s starter Carlos Zambrano. The Cubs sent pitcher Sean Gallagher, catcher Josh Donaldson, infielder Eric Patterson and outfielder Matt Murton to the A’s for Harden and pitcher Chad Gaudin.

Check out the current line for this game at SBG Global.

Zambrano is still the ace of the Cubs staff and he gets the start on Wednesday against the Reds. Zambrano is 9-3 on the season with a 2.96 ERA. He threw six shutout innings in his last start against St. Louis. He is already 2-0 against the Red this year.

Cincinnati goes with Johnny Cueto on Wednesday. Cueto is 7-8 with a 4.63 ERA. He gave up three runs in seven innings against the Nationals in his last start. He has pitched well of late, giving up only six runs in his last four starts. He has pitched once in his career against the Cubs going six innings, allowing three runs and six hits.

Here are the MLB betting stats for Wednesday’s game. The Reds are 4-1 in their last 5 games vs. a right-handed starter. The Reds are 7-16 in their last 23 games as a road underdog. The Reds are 2-5 in their last 7 vs. the National League Central. The Reds are 2-5 in Cueto’s last 7 starts as an underdog. The Reds are 2-6 in Cueto’s last 8 road starts. The Reds are 2-5 in the last 7 meetings in Chicago.

The Cubs are 41-12 in their last 53 games as a home favorite. The Cubs are 9-4 in their last 13 Wednesday games. The Cubs are 43-21 in their last 64 home games vs. a right-handed starter. The Cubs are 6-2 in Zambrano’s last 8 starts as a home favorite. The Cubs are 2-5 in Zambrano’s last 7 home starts vs. the Reds.

The Under is 11-5-1 in the Reds last 17 road games vs. a right-handed starter. The Under is 4-0 in Cueto’s last 4 starts overall.

The Over is 4-1 in the Cubs last 5 games as a home favorite. The Over is 12-4 in the Cubs last 16 games vs. a right-handed starter. The Under is 8-3 in Zambrano’s last 11 starts as a home favorite. The Over is 4-1 in Zambrano’s last 5 home starts vs. the Reds. The Over is 7-2 in the last 9 meetings in Chicago between the two teams.