Mike Leake (11-13, 3.70 ERA) and Gerrit Cole (11-5, 3.65 ERA) are on the hill in the second of a three-game series between the Cincinnati Reds (1-0) and the Pittsburgh Pirates (0-1) at the Great American Ball Park. The Reds won the last game 5-2 and Cincinnati leads the series 1-0. Action begins at 7:10 p.m. ET on Wednesday, Apr. 8 and can be seen on ROOT-PIT and FSN-OH.

Leake is 6-3 with a 3.22 ERA, 1.25 WHIP, and 81 strikeouts against the Pirates. Joey Votto (.500 ) kept up his hot start Monday, going 2 for 4 with one run. When pitching against the Reds, Cole is 0-1 with a 4.15 ERA, 1.23 WHIP, and 15 strikeouts. Andrew McCutchen (.500 ) has been successful at the plate to the start the season for the Pirates, going 2 for 4 Monday with one run, one home run, and two RBIs.

Cincinnati is a narrow -106 favorite at home against Pittsburgh. The Over/Under (O/U) is sitting at seven runs for this matchup.

The Reds have the edge in the season series, 1-0.

Predictions: SU Winner - CIN, O/U - Over

Notes

Pittsburgh is 1-4 SU in its last 5 games.

Pittsburgh is 17-8 SU in its last 25 games.

Pittsburgh is 10-5 SU in its last 15 games on the road.

Pittsburgh is 2-4 SU in its last 6 games on the road.

The total has gone UNDER in 5 of Pittsburgh's last 7 games when playing Cincinnati.

Pittsburgh is 1-4 SU in its last 5 games when playing Cincinnati.

Pittsburgh is 1-4 SU in its last 5 games when playing on the road against Cincinnati.