white sox indians mlb picksHector Noesi (0-1, 3.86 ERA) and the Chicago White Sox (5-7) go up against Carlos Carrasco (1-1, 2.84 ERA) and the Cleveland Indians (4-8) in the second of a three-game division series at U.S. Cellular Field. The White Sox won the last game 4-3 and Chicago leads the series 1-0. The game starts at 8:10 p.m. ET on Tuesday, Apr. 21 and will air on STO and CSN-CHI.

Noesi is 1-1 with a 4.23 ERA against the Indians in his career, and is up against a struggling Cleveland offense that's hitting just .218 on the year. Avisail Garcia (.308, 7 Rs, 1 HR, 3 RBIs, 1 SB) continued his strong start to the season yesterday, going 2 for 4 with one run. Carlos Carrasco returns to the mound after the scary line drive from Melky Cabrera that hit him in the face last week. Mike Aviles (.280, 4 Rs, 1 HR, 1 RBI) has been doing well to start the season for the Indians, going 2 for 3 yesterday with one run.

Chicago is a +109 underdog in this game and the Over/Under (O/U) is eight runs. The White Sox perform poorly as an underdog with a 2-6 record and have an overall money line of -293.

On the other side, the Indians have a subpar record of 2-5 when they are favored and are -448 overall with the money line. Against divisional opponents, they are 2-6 SU and have played poorly as the favorite with a 1-5 record. When it comes to scoring runs, the Indians have performed much better than normal against teams from the AL Central. During those games, they averaged three runs per game, above their 3.2 season average. Cleveland's pitching staff and defense as a whole has been firing on all cylinders so far, averaging an AL-best two runs allowed per road game. They also average just 5.2 hits allowed per road game, best in the AL. The Cleveland pitching staff has been an intimidating group on the road this year, averaging an AL-best 10.8 strikeouts per game.

In their previous three games this season, the White Sox have a 2-1 record. The White Sox will take on a right-hander (Bauer) in this game and have a 4-4 record against right-handed starting pitchers this season. Taking the hill against the Indians will be the right-hander Noesi. They sport a 3-3 record against righties.

Predictions: SU Winner - CWS, O/U - Over


The Indians currently sit below .500 against the AL Central Division at 2-7, and the White Sox have a 5-7 record.

Chicago has lost all of its games (0-2) when leading after 7 innings. However, Cleveland has won 50% (2-2) of its games when taking a late lead.

The Chicago batters brought in a solid 10 hits last game. Cleveland has a record of 0-5 when their opponents get that many hits or more.

When outhit, both the White Sox and the Indians have records of 0-7.

Ranking 23rd in home runs, Cleveland has hit nine this season. Chicago ranks 19th with 10 home runs.

Ranking 11th, Cleveland is in the top half of the league in hits, notching 7.45 per game. Chicago ranks in the top 10 at ninth with 7.82.

Ranking 27th, Cleveland is near the bottom of the league for its on-base plus slugging percentage (.610). Chicago ranks in the bottom half at 18th with an OPS of .680.

When the Indians allow at least one home run, the team is 2-6. Chicago has the same record when it allows one or more homers.