Barry Zito (0-0, 18.00 ERA) and Tim Hudson (8-8, 4.20 ERA) take the hill in the second of a three-game series between the Oakland Athletics (65-89) and the San Francisco Giants (79-74) at O.co Coliseum. The Athletics won the last game 5-4 and Oakland leads the series 1-0. Action begins at 4:05 p.m. ET on Saturday, Sep. 26 and can be seen on CSCA, CSBy and MLBN.

Zito pitched 1.0 innings in his most recent start, surrendering two runs and walking one in a 5-1 defeat to the Astros. Danny Valencia (.290, 52 Rs, 16 HRs, 61 RBIs, 2 SBs) went 1 for 4 yesterday with one run. Hudson went 6.0 innings, surrendering zero runs, striking out three and walking three in a 5-1 win over the Diamondbacks in his last outing. Buster Posey (.323, 72 Rs, 19 HRs, 93 RBIs, 2 SBs) has been successful at the plate, going 2 for 4 yesterday.

San Francisco takes on Oakland as a -135 favorite. The Over/Under (O/U) for the matchup is sitting at eight runs. The Athletics have recorded an overall money line of -3,041 and have shown a weak performance as an underdog this season with a record of 31-52. Against the NL, they have had a solid season, earning 7-5 and 10-7 records as the underdog and SU respectively. The Athletics have seen an uptick in scoring against teams in the NL, averaging 4.9 runs per game. They average 4.2 runs per game on the season. Oakland's batters do not strike out very often, with only 6.8 per game. Oakland's pitching staff has been doing poorly against opposing offenses during the last 10 games, allowing an average of 6.9 runs per game, well above its season average of 4.4.

In games where it is the favorite, San Francisco has a 46-33 record and an overall money line of -80. San Francisco has put in a great performance against teams in the AL, coming in with a nice record SU ({betdsi.at.al.su_record}) and as the favorite (7-3). Offensively, they average 4.3 runs per game, which is good for fifth in the NL. The Giants allow 3.8 runs per game, but does better whenever an AL opponent is on the schedule. They bring that runs allowed average down to 2.6 against teams from the AL.

The Giants lead the season series, 3-1. The Athletics have a 50-57 record against right-handed starting pitchers on the year, which is what they'll be facing when Hudson takes the mound. Zito (LHP) will be on the hill against the Giants, who have an 18-20 record against left-handed starting pitchers.

Predictions: SU Winner - SF, O/U - Over

Notes

The Giants lost their last game by a one-run margin. In games decided by one run, the Athletics are 18-32. The Giants are 16-27 in close games this season.

The Athletics are coming off of a hot pitching game where they recorded nine strikeouts. The Giants have a record of 24-22 when they are struck out that many times or more.

When they are outhit, the Giants are 5-48. The Athletics have an 11-59 record when opponents outhit them.

San Francisco ranks near the bottom of the league at 27th when it comes to home runs, hitting 128 this season. Oakland ranks in the bottom half at 20th with 139.

Ranking seventh, Oakland is in the top 10 of the league in hits, notching 8.69 per game. San Francisco ranks in the top five at second with 9.18.

Ranking 23rd, Oakland is near the bottom of the league for its on-base plus slugging percentage (.709). San Francisco ranks in the top half at 11th with an OPS of .736.

When the Giants allow at least one home run, they are 37-54. When the Athletics allow one or more homers, they have a 27-68 record.