All 30 teams are back in action when the MLB continues on Wednesday, September 14, and we have an inter-league clash that is do-or-die for the hosts, so make sure you don’t miss out on the best Rockies vs. White Sox betting pick and odds.

Colorado and Chicago will play the second of a two-game series at Guaranteed Rate Field and the White Sox are strong -227 moneyline favorites on MyBookie Sportsbook, while the total is set at 7.5 runs. These interleague rivals have faced two times this season, and each team secured a win. Game 1 of the series will be played on Tuesday night.

Rockies failed to sweep the D-Backs

The Colorado Rockies were on a four-game winning streak and wanted to make it five in a row and sweep the divisional foes Arizona Diamondbacks at home, but couldn’t do it. Colorado beat Arizona in the first two games of the series, scoring 17 runs in the process, but the D-Backs were better in Game 3 and celebrated a 12-6 victory.

Colorado did break Zac Gallen’s shutout streak that lasted 44 1/3 innings through C.J. Cron, while Ryan McMahon hit a home run, but Arizona scored nine runs in two innings (3rd and 7th) and deservedly got its win. Ryan Feltner (2-8) took a loss after surrendering four runs on four hits with three strikeouts and four walks over 2.2 innings.

Kyle Freeland (8-9) will get to the hill for the 28th time this year when he faces the White Sox on Wednesday. The 29-year-old left-hander has a 4.63 ERA, 1.37 WHIP, and 112/46 K/BB ratio across 153.2 innings.

White Sox returned home with a smile on their faces

The Chicago White Sox are back home from a seven-game road trip on the West, on which they met the Seattle Mariners and Oakland Athletics. Chicago won five of those games and is still alive in the race for the AL Central title. They are two wins behind the Cleveland Guardians but have played two games more, so the White Sox must win this one against Colorado.

Chicago did win the opening three games of the series against the Oakland Athletics but failed to sweep it as they lost 10-3 in Game 4. The White Sox actually had a 2-1 lead until the bottom 5th when Oakland scored six runs. Johnny Cueto struggled in his start as he allowed five runs on eight hits with three strikeouts and a walk in 4.2 innings.

Dylan Cease (14-6) is getting his 29th start of the year when he takes on Colorado on Wednesday. The 26-year-old righty is enjoying the best season of his career and will carry a sublime 2.06 ERA and 1.07 WHIP into this duel, while he has a 206/66 K/BB ratio in 162.0 innings.



  • 3-8 in the last 11 interleague games
  • 2-6 in the last eight games vs. a right-handed starter
  • 2-7 in the last nine vs. American League Central rivals


  • 4-0 in the last four games vs. a starter with a WHIP greater than 1.30
  • 5-1 in the last six vs. a team with a losing record

Colorado Rockies vs. Chicago White Sox Pick

Chicago cannot lose games against teams with a losing record and must beat the Rockies if they want to keep up with Cleveland. It’s tight in the AL Central, with the Twins also in the mix, and it’s possible that only the champions of this division will enter the postseason. The White Sox are strong against southpaws, averaging .281 with 5.28 runs over nine innings. Colorado is playing without pressure, which can be dangerous for the hosts, but the White Sox know what they have to do and their recent form is encouraging.

Pick: Take the White Sox at -1.5 Run Line (-110)

The Total

Kyle Freeland displayed a couple of excellent starts to open this month as he allowed just one run in each despite allowing ten hits. And what to say about Dylan Cease, who fired 15 shutout innings against Minnesota and Oakland and is one of the hottest pitchers in the MLB right now and a clear AL Cy Young candidate. With pitchers in such good form, I expect a low-scoring affair here. Under is 4-0 in Cease’s last four home starts vs. a team with a losing record, while Under is 4-0 in the previous four H2H meetings.

Pick: Go Under 7.5 runs (-110)