The 2022 NFL season goes on Sunday, September 18, with Week 2 matchups, including the interconference showdown from AT&T Stadium in Arlington, Texas, so we bring you the best Bengals vs. Cowboys betting pick and odds. 

Cincinnati meets Dallas for the first time since December 2020 when the Cowboys trounced the Bengals 30-7 as 3-point road favorites. Dallas is a 7-point home underdog this time around, while Cincy is a -325 moneyline fave with a total of 50.5 points on Bookmaker Sportsbook

The Bengals suffered a tough, surprising loss in Week 1                                      

The Cincinnati Bengals nearly overcame an 11-point halftime deficit at the start of the season but eventually suffered a 23-20 overtime loss to the Pittsburgh Steelers. Playing as firm 7-point home favorites, the reigning AFC champions outgained the Steelers 432-267 in total yards. However, the Bengals lost the turnover battle 5-0, while Evan McPherson missed a 29-yard field goal in overtime. 

Joe Burrow had an awful Week 1, finishing 33-of-53 for 338 yards, a couple of touchdowns, and a whopping four interceptions. He also lost a fumble to round up an abysmal performance. And in spite of Burrow’s ignominy, the Bengals were so close to pulling off the victory against the resilient Steelers defense. 

Burrow also had six carries for 47 yards, while Joe Mixon posted 27 totes for 82 yards. Mixon added seven receptions for 63 yards, Tyler Boys had four catches for 33 yards and a touchdown, and Ja’Marr Chase caught ten of his 16 targets for 129 yards and a TD. Tee Higgins suffered a concussion and is questionable to play in Week 2.  

The Cowboys were awful in their season opener          

The Dallas Cowboys started the 2022 NFL season with a 19-3 home loss to Tom Brady and the Tampa Bay Buccaneers. Brett Maher gave the Cowboys an early lead with a 51-yard field goal, but that was all we saw from Dallas’ offense. The Cowboys racked up just 244 total yards and didn’t make it to the red zone once which tells you enough about their performance. 

Dak Prescott was 14-of-29 for 134 yards and a pick. He suffered a hand injury and will miss multiple weeks, so Cooper Rush will start under center in Week 2. Rush completed seven of his 13 passing attempts for 64 yards against the Buccaneers, while Ezekiel Elliott had ten carries for 52 yards. Elliott and Tony Pollard, who ran six times for a paltry eight yards in Week 1, will have to step up in Prescott’s absence. 

On the other side of the ball, the Cowboys allowed the Bucs to record 152 rushing yards and 4.6 yards per carry. They picked off Brady once, but the Cowboys’ run defense showed a lot of flaws. Furthermore, Dallas committed ten penalties for 73 yards and allowed four sacks for 25 yards. 



  • 8-1 ATS in the last nine games overall 
  • 5-0 ATS in the last five games on the road  


  • 1-4 ATS in the last five games at home 

Cincinnati Bengals vs. Dallas Cowboys Pick 

The Bengals will roll over Dallas. Their offensive line will be too much for the Cowboys’ run D, and I’m expecting Joe Mixon to get 20-plus carries once more. Joe Burrow can only play better than he did in Week 1, so give me the Bengals and points. 

Cincinnati’s defense played well last weekend, and I’m looking for more of the same against Prescot-less Dallas. Cooper Rush will be under huge pressure given the way the Cowboys’ O-line played against Tampa Bay. 

Pick: Take Cincinnati Bengals -7.0 at -110                                  

The Total:

The Cowboys’ secondary is arguably the best part of their team. The Bengals will have to lean on their rushing offense to move the ball frequently, and the Cowboys have to do the same now Dak Prescott is on the shelf. 

As I’ve mentioned above, the Bengals should shut down the Cowboys’ offense. The total has gone under in Cincinnati’s last six outings, and I would ride this betting trend. Also, the under is 10-3 in the Cowboys’ previous 13 showings at any location. 

Pick: Go under 50.5 points at -110