San Diego at Pittsburgh (-9.5, 40)
The Steelers will have quarterback Ben Roethlisberger (shoulder) back under center when they host San Diego. The Steelers have won seven of the past eight meetings with the Chargers - and 14 straight in Pittsburgh - and San Diego coach Norv Turner is 0-6 against Pittsburgh. San Diego hasn’t cracked 300 total yards in its past three games and QB Philip Rivers is having perhaps his worst season as a starter, having thrown 15 interceptions against 18 touchdowns. Pittsburgh has held seven straight opponents under 300 total yards, allowing an average of 234 yards during that stretch. The Steelers are 1-5 ATS in their last six against teams with losing records.