Pittsburgh at South Florida (7, 46.5)
The Panthers have shown a tendency to play to the level of their competition this season. Pitt is coming off a huge victory over Rutgers (its second win against a ranked opponent at the time), just two weeks after taking Notre dame to triple overtime. The Panthers have an opportunity to become bowl eligible with a victory and won’t be lacking motivation this weekend. South Florida is devastated by injuries at the QB position. Freshman Matt Floyd has yet to throw a touchdown pass in two starts and has led the offense to a total of 19 points in back-to-back losses at Miami and Cincinnati. The Panthers are 4-1 ATS in their last five games overall.