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Colin Kaepernick is expected to be under center Sunday when the 49ers look to extend their winning streak to five games against visiting New Orleans. Drew Brees leads a Saints team that has reeled off three straight victories and is 5-1 since opening the year with four straight losses. But he'll be in tough against a San Francisco defense allowing the second-fewest passing yards in the league. Saints RB Darren Sproles (hand) has been participating in practice and is expected to return after missing the last three weeks of action. New Orleans is 6-1 ATS in its last seven overall.
After a bit of a slow start, Aaron Rodgers has heated up as the Packers have won five straight and six of seven. He leads the NFL with a 107.3 QB rating and has 27 touchdown passes against six interceptions. The Packers haven't been able to mount much of a run game, but they're more likely to attack the Giants through the air, as New York ranks 25th against the pass and surrendered 415 passing yards against Dallas in Week 8. Green Bay's defense will be shorthanded with CB Charles Woodson out with a broken collarbone and LB Clay Matthews (hamstring) listed as questionable. The Giants are coming off a bye week and have lost two straight and may be without RB Ahmad Bradshaw (foot). These teams have played over the total in their last five meetings.