Texas Rangers at Boston Red Sox Preview 8/13/2008
Posted by admin on August 13, 2008 · Leave a Comment
MLB Betting Preview
Texas Rangers at Boston Red Sox
Wednesday, 7:05 pm Eastern – ESPN
SBG Global Opening Line: Red Sox – 230 , Total 10 Under – 120
The Boston Red Sox are heavy favorites on Wednesday as they host the Texas Rangers and Jon Lester is the big reason why. He is 10-4 on the season with a 3.23 ERA. He is 6-1 at home this season with a 2.87 ERA in 12 starts. He will be opposed by Luis Mendoza who is 3-5 with a 7.50 ERA this season. Mendoza is 1-2 with a 7.50 ERA in his four starts since the All-Star break. He is 1-3 with an 8.46 ERA on the road. He was shelled earlier this year at Boston by a score of 11-3. SBG Global reports that early MLB betting has the public taking Red Sox at Home.
Here are the MLB betting stats for Wednesday’s game. The Rangers are 16-37 in their last 53 road games vs. a left-handed starter. The Rangers are 1-4 in their last 5 vs. the American League East. The Rangers are 1-4 in their last 5 games as an underdog. The Rangers are 1-4 in their last 5 overall. The Rangers are 3-7 in Mendoza’s last 10 starts. The Rangers are 1-4 in Mendoza’s last 5 starts vs. the American League East. The Rangers are 1-7 in Mendoza’s last 8 starts as an underdog. The Rangers are 0-5 in Mendoza’s last 5 road starts. The Rangers are 9-31 in the last 40 meetings in Boston.
SBG Global Current Line: Red Sox – 240 , Total 10.5 Over – 125
The Red Sox are 51-17 in their last 68 games as a home favorite. The Red Sox are 45-17 in their last 62 home games vs. a right-handed starter. The Red Sox are 7-3 in their last 10 overall. The Red Sox are 18-4 in Lester’s last 22 starts as a home favorite.
The Over is 5-0-1 in the Rangers last 6 games vs. a left-handed starter. The Under is 4-1 in the Rangers last 5 vs. the American League East. The Under is 4-1 in the Rangers last 5 overall. The Over is 4-1 in Mendoza’s last 5 starts as a road underdog.
The Under is 5-2 in the Red Sox last 7 games as a favorite. The Over is 4-1 in Lester’s last 5 starts as a home favorite. The Under is 5-2 in Lester’s last 7 starts vs. the American League West.
Pick: Rangers +200 1 unit
Alterations to the lymphatic system in Hodgkin’s Disease.(Fast Facts)
Journal of Continuing Education Topics & Issues August 1, 2007 | Boe, Gerard P.
Hodgkin’s Disease was first described by Thomas Hodgkin in 1832. It accounts for 40% of all lymphomas and 1% of all cancers. Hodgkin’s lymphoma differs from non-Hodgkin’s lymphoma in the following ways:
1. Predictable contiguous spread from one chain of lymph node groups to another 2. Presence of the Hodgkin/Reed-Sternberg cell (HRS) 3. Cells other than lymphocytes may be present in the lymph nodes or white pulp (lymphoid area) of the spleen 4. Never exhibits a leukemia phase The changes that occur in the lymphatic system in Hodgkin’s Disease can be divided into these categories: hodgkinsdiseasenow.net hodgkin s disease
1. Anatomic 2. Histologic 3. Immune Function Anatomic Changes The physical changes that may occur include an enlarged spleen and enlarged lymph nodes. If the spleen is involved and becomes enlarged, it usually means there is hematologic spread and may include the liver and the bone marrow. The extent of the disease can sometimes be determined by the number of lymph nodes affected. It can vary from one lymph node to one lymphatic site to multiple nodes and multiple sites.
Histologic Changes One or more of the following may be present: fibrosis, a depletion of lymphocytes, and increase in eosinophils and the large REED-STERNBERG or HODGKINS cells. The Reed-Sternberg cells are binucleated or multi-nucleated and must be present to make the diagnosis of Hodgkin’s Disease. In Hodgkin’s, the lymphocytes, eosinophils, plasma cells and macrophages that may be present often surround the Hodgkin/Reed-Sternberg cell.
In other disorders where the Reed-Sternberg cell is found, the other elements do not surround the cell. For this reason, it is important to recognize that the presence of Reed-Sternberg cells is not always diagnostic of Hodgkin’s Disease.
Using molecular analysis, research has shown the presence of the Epstein Barr Virus(EBV) in the Reed-Sternberg and Hodgkin’s cells in about one-half (50%) of cases. Thus, EB virus is likely to be involved in at least a subset of cases of Hodgkin’s Disease.
Immune Function Cellular immunity is defective in Hodgkin’s lymphoma. Cellular immunity involves the production and function of T cells. Impaired delayed cutaneous hypersensitivity, decreased natural killer cell cytotoxicity, enhanced suppressor T cell and suppressor monocyte activity are among the abnormalities which may be observed. go to site hodgkin s disease
It is well documented that increased susceptibility to opportunistic infections increases when there is impairment of the T cells.
Humoral immunity–the function of B cells is usually normal in untreated patients with Hodgkin’s disease Both radiation and chemotherapy temporarily reduce the number of B cells. This system returns to normal when the course of treatment is completed, the exception being those patients in the advanced stages of the disease.
References Bellanti, Joseph A. ed., Clinical Immunology, Philadelphia: W.B. Saunders Co., 1994 Hardin, Robert I., ed., et. al., Blood: Principles and Practice of Hematology, Philadelphia: Lippincott, 1995 This “Fast Facts” article was prepared by Gerard P. Boe, PhD, CLC(AMT), MT(AMT), Executive Director of American Medical Technologists’ Institute for Education (AMTIE), Editor of AMT Journal of Continuing Education Topics & Issues, and Chair, AMT CLC Evaluation Committee.
Boe, Gerard P.
